NEUR4_HUMAN   Q8WWR8


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UniProt:Q8WWR8

Recommended name:Sialidase-4

EC number:EC:3.2.1.18

Alternative names:(N-acetyl-alpha-neuraminidase 4)

Cleaved into:

GeneID:129807

Gene names  (primary ):NEU4

Gene names  (synonym ):

Gene names  (ORF ):LP5125

Length:484

Mass:51572

Sequence:MGVPRTPSRTVLFERERTGLTYRVPSLLPVPPGPTLLAFVEQRLSPDDSHAHRLVLRRGTLAGGSVRWGALHVLGTAALAEHRSMNPCPVHDAGTGTVFLFFIAVLGHTPEAVQIATGRNAARLCCVASRDAGLSWGSARDLTEEAIGGAVQDWATFAVGPGHGVQLPSGRLLVPAYTYRVDRRECFGKICRTSPHSFAFYSDDHGRTWRCGGLVPNLRSGECQLAAVDGGQAGSFLYCNARSPLGSRVQALSTDEGTSFLPAERVASLPETAWGCQGSIVGFPAPAPNRPRDDSWSVGPGSPLQPPLLGPGVHEPPEEAAVDPRGGQVPGGPFSRLQPRGDGPRQPGPRPGVSGDVGSWTLALPMPFAAPPQSPTWLLYSHPVGRRARLHMGIRLSQSPLDPRSWTEPWVIYEGPSGYSDLASIGPAPEGGLVFACLYESGARTSYDEISFCTFSLREVLENVPASPKPPNLGDKPRGCCWPS

Tissue specificity:[Isoform 1]: Predominant form in liver. Also expressed in brain, kidney and colon. {ECO:0000269|PubMed:14962670, ECO:0000269|PubMed:15847605}.; [Isoform 2]: Highly expressed in brain and at lower levels in kidney and liver. {ECO:0000269|PubMed:15847605}.

Induction:Down-regulated during monocyte to macrophage differentiation. {ECO:0000269|PubMed:15885103}.

Developmental stage:

Protein families:Glycosyl hydrolase 33 family


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