MCL1_HUMAN Q07820
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UniProt:Q07820
Recommended name：Induced myeloid leukemia cell differentiation protein Mcl-1
EC number：
Alternative names：(Bcl-2-like protein 3) (Bcl2-L-3) (Bcl-2-related protein EAT/mcl1) (mcl1/EAT)
Cleaved into：
GeneID：4170
Gene names (primary )：MCL1
Gene names (synonym )：BCL2L3
Gene names (ORF )：
Length：350
Mass：37337
Sequence：MFGLKRNAVIGLNLYCGGAGLGAGSGGATRPGGRLLATEKEASARREIGGGEAGAVIGGSAGASPPSTLTPDSRRVARPPPIGAEVPDVTATPARLLFFAPTRRAAPLEEMEAPAADAIMSPEEELDGYEPEPLGKRPAVLPLLELVGESGNNTSTDGSLPSTPPPAEEEEDELYRQSLEIISRYLREQATGAKDTKPMGRSGATSRKALETLRRVGDGVQRNHETAFQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISFGAFVAKHLKTINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFFHVEDLEGGIRNVLLAFAGVAGVGAGLAYLIR
Tissue specificity：
Induction：Expression increases early during phorbol ester-induced differentiation along the monocyte/macrophage pathway in myeloid leukemia cell line ML-1. Rapidly up-regulated by CSF2 in ML-1 cells. Up-regulated by heat shock-induced differentiation. Expression increases early during retinoic acid-induced differentiation. {ECO:0000269|PubMed:8790944, ECO:0000269|PubMed:9671497}.
Developmental stage：
Protein families：Bcl-2 family