UB2R1_HUMAN P49427
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UniProt:P49427
Recommended name:Ubiquitin-conjugating enzyme E2 R1
EC number:EC:2.3.2.23
Alternative names:((E3-independent) E2 ubiquitin-conjugating enzyme R1) (E2 ubiquitin-conjugating enzyme R1) (Ubiquitin-conjugating enzyme E2-32 kDa complementing) (Ubiquitin-conjugating enzyme E2-CDC34) (Ubiquitin-protein ligase R1)
Cleaved into:
GeneID:997
Gene names (primary ):CDC34
Gene names (synonym ):UBCH3 UBE2R1
Gene names (ORF ):
Length:236
Mass:26737
Sequence:MARPLVPSSQKALLLELKGLQEEPVEGFRVTLVDEGDLYNWEVAIFGPPNTYYEGGYFKARLKFPIDYPYSPPAFRFLTKMWHPNIYETGDVCISILHPPVDDPQSGELPSERWNPTQNVRTILLSVISLLNEPNTFSPANVDASVMYRKWKESKGKDREYTDIIRKQVLGTKVDAERDGVKVPTTLAEYCVKTKAPAPDEGSDLFYDDYYEDGEVEEEADSCFGDDEDDSGTEES
Tissue specificity:Expressed in testes during spermatogenesis to regulate repression of cAMP-induced transcription. {ECO:0000269|PubMed:10373550}.
Induction:Negatively regulated by the let-7 microRNA. {ECO:0000269|PubMed:19126550}.
Developmental stage:
Protein families:Ubiquitin-conjugating enzyme family