UB2R1_HUMAN   P49427


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UniProt:P49427

Recommended name:Ubiquitin-conjugating enzyme E2 R1

EC number:EC:2.3.2.23

Alternative names:((E3-independent) E2 ubiquitin-conjugating enzyme R1) (E2 ubiquitin-conjugating enzyme R1) (Ubiquitin-conjugating enzyme E2-32 kDa complementing) (Ubiquitin-conjugating enzyme E2-CDC34) (Ubiquitin-protein ligase R1)

Cleaved into:

GeneID:997

Gene names  (primary ):CDC34

Gene names  (synonym ):UBCH3 UBE2R1

Gene names  (ORF ):

Length:236

Mass:26737

Sequence:MARPLVPSSQKALLLELKGLQEEPVEGFRVTLVDEGDLYNWEVAIFGPPNTYYEGGYFKARLKFPIDYPYSPPAFRFLTKMWHPNIYETGDVCISILHPPVDDPQSGELPSERWNPTQNVRTILLSVISLLNEPNTFSPANVDASVMYRKWKESKGKDREYTDIIRKQVLGTKVDAERDGVKVPTTLAEYCVKTKAPAPDEGSDLFYDDYYEDGEVEEEADSCFGDDEDDSGTEES

Tissue specificity:Expressed in testes during spermatogenesis to regulate repression of cAMP-induced transcription. {ECO:0000269|PubMed:10373550}.

Induction:Negatively regulated by the let-7 microRNA. {ECO:0000269|PubMed:19126550}.

Developmental stage:

Protein families:Ubiquitin-conjugating enzyme family


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