ASAH1_HUMAN Q13510
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UniProt:Q13510
Recommended name:Acid ceramidase
EC number:EC:3.5.1.23
Alternative names:(AC) (ACDase) (Acid CDase) (Acylsphingosine deacylase) (N-acylethanolamine hydrolase ASAH1) (N-acylsphingosine amidohydrolase) (Putative 32 kDa heart protein) (PHP32)
Cleaved into:Acid ceramidase subunit alpha; Acid ceramidase subunit beta
GeneID:427
Gene names (primary ):ASAH1
Gene names (synonym ):ASAH
Gene names (ORF ):HSD-33 HSD33
Length:395
Mass:44660
Sequence:MPGRSCVALVLLAAAVSCAVAQHAPPWTEDCRKSTYPPSGPTYRGAVPWYTINLDLPPYKRWHELMLDKAPVLKVIVNSLKNMINTFVPSGKIMQVVDEKLPGLLGNFPGPFEEEMKGIAAVTDIPLGEIISFNIFYELFTICTSIVAEDKKGHLIHGRNMDFGVFLGWNINNDTWVITEQLKPLTVNLDFQRNNKTVFKASSFAGYVGMLTGFKPGLFSLTLNERFSINGGYLGILEWILGKKDVMWIGFLTRTVLENSTSYEEAKNLLTKTKILAPAYFILGGNQSGEGCVITRDRKESLDVYELDAKQGRWYVVQTNYDRWKHPFFLDDRRTPAKMCLNRTSQENISFETMYDVLSTKPVLNKLTVYTTLIDVTKGQFETYLRDCPDPCIGW
Tissue specificity:Broadly expressed with higher expression in heart. {ECO:0000269|PubMed:10610716}.
Induction:Up-regulated by Ca(2+). {ECO:0000269|PubMed:17713573}.
Developmental stage:
Protein families:Acid ceramidase family