ASAH1_HUMAN   Q13510


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UniProt:Q13510

Recommended name:Acid ceramidase

EC number:EC:3.5.1.23

Alternative names:(AC) (ACDase) (Acid CDase) (Acylsphingosine deacylase) (N-acylethanolamine hydrolase ASAH1) (N-acylsphingosine amidohydrolase) (Putative 32 kDa heart protein) (PHP32)

Cleaved into:Acid ceramidase subunit alpha; Acid ceramidase subunit beta

GeneID:427

Gene names  (primary ):ASAH1

Gene names  (synonym ):ASAH

Gene names  (ORF ):HSD-33 HSD33

Length:395

Mass:44660

Sequence:MPGRSCVALVLLAAAVSCAVAQHAPPWTEDCRKSTYPPSGPTYRGAVPWYTINLDLPPYKRWHELMLDKAPVLKVIVNSLKNMINTFVPSGKIMQVVDEKLPGLLGNFPGPFEEEMKGIAAVTDIPLGEIISFNIFYELFTICTSIVAEDKKGHLIHGRNMDFGVFLGWNINNDTWVITEQLKPLTVNLDFQRNNKTVFKASSFAGYVGMLTGFKPGLFSLTLNERFSINGGYLGILEWILGKKDVMWIGFLTRTVLENSTSYEEAKNLLTKTKILAPAYFILGGNQSGEGCVITRDRKESLDVYELDAKQGRWYVVQTNYDRWKHPFFLDDRRTPAKMCLNRTSQENISFETMYDVLSTKPVLNKLTVYTTLIDVTKGQFETYLRDCPDPCIGW

Tissue specificity:Broadly expressed with higher expression in heart. {ECO:0000269|PubMed:10610716}.

Induction:Up-regulated by Ca(2+). {ECO:0000269|PubMed:17713573}.

Developmental stage:

Protein families:Acid ceramidase family


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