DAPK2_HUMAN Q9UIK4
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UniProt:Q9UIK4
Recommended name:Death-associated protein kinase 2
EC number:EC:2.7.11.1
Alternative names:(DAP kinase 2) (DAP-kinase-related protein 1) (DRP-1)
Cleaved into:
GeneID:23604
Gene names (primary ):DAPK2
Gene names (synonym ):
Gene names (ORF ):
Length:370
Mass:42898
Sequence:MFQASMRSPNMEPFKQQKVEDFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVSREEIEREVSILRQVLHHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSFIKQILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANITAVSYDFDEEFFSQTSELAKDFIRKLLVKETRKRLTIQEALRHPWITPVDNQQAMVRRESVVNLENFRKQYVRRRWKLSFSIVSLCNHLTRSLMKKVHLRPDEDLRNCESDTEEDIARRKALHPRRRSSTS
Tissue specificity:Expressed in neutrophils and eosinophils (PubMed:24163421). Isoform 2 is expressed in embryonic stem cells (at protein level). Isoform 1 is ubiquitously expressed in all tissue types examined with high levels in heart, lung and skeletal muscle. {ECO:0000269|PubMed:10376525, ECO:0000269|PubMed:17347302, ECO:0000269|PubMed:21408167, ECO:0000269|PubMed:24163421}.
Induction:Up-regulated during granulocytic maturation (PubMed:17347302, PubMed:24163421). {ECO:0000269|PubMed:17347302, ECO:0000269|PubMed:24163421}.
Developmental stage:
Protein families:Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily