NTCP7_HUMAN Q0GE19
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UniProt:Q0GE19
Recommended name:Sodium/bile acid cotransporter 7
EC number:
Alternative names:(Na(+)/bile acid cotransporter 7) (Solute carrier family 10 member 7)
Cleaved into:
GeneID:84068
Gene names (primary ):SLC10A7
Gene names (synonym ):C4orf13 P7
Gene names (ORF ):PSEC0051
Length:340
Mass:37432
Sequence:MRLLERMRKDWFMVGIVLAIAGAKLEPSIGVNGGPLKPEITVSYIAVATIFFNSGLSLKTEELTSALVHLKLHLFIQIFTLAFFPATIWLFLQLLSITPINEWLLKGLQTVGCMPPPVSSAVILTKAVGGNEAAAIFNSAFGSFLGIVITPLLLLLFLGSSSSVPFTSIFSQLFMTVVVPLIIGQIVRRYIKDWLERKKPPFGAISSSVLLMIIYTTFCDTFSNPNIDLDKFSLVLILFIIFSIQLSFMLLTFIFSTRNNSGFTPADTVAIIFCSTHKSLTLGIPMLKIVFAGHEHLSLISVPLLIYHPAQILLGSVLVPTIKSWMVSRQKGVKLTRPTV
Tissue specificity:Widely expressed (PubMed:15932064, PubMed:17628207). Expressed at high levels in liver and at lower levels in prostate, placenta, kidney, heart, lung, thymus and spleen (PubMed:15932064, PubMed:17628207). Strongly expressed in testis and also detected in brain, ovary, colon and small intestine (PubMed:17628207). Weakly expressed in testis and not detected in brain, ovary, colon or small intestine (PubMed:15932064). Isoform 1: Expressed in liver, testis and placenta (PubMed:17628207). Isoform 4: Expressed in liver, testis and placenta (PubMed:17628207). {ECO:0000269|PubMed:15932064, ECO:0000269|PubMed:17628207}.
Induction:
Developmental stage:Detected in the heart and vertebrae in embryos at 8 weeks of gestation (Carnegie stage 16), and in the long-bone cartilage at 9 weeks (Carnegie stages 19). {ECO:0000269|PubMed:30082715}.
Protein families:Bile acid:sodium symporter (BASS) (TC 2.A.28) family