NTCP7_HUMAN   Q0GE19


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UniProt:Q0GE19

Recommended name:Sodium/bile acid cotransporter 7

EC number:

Alternative names:(Na(+)/bile acid cotransporter 7) (Solute carrier family 10 member 7)

Cleaved into:

GeneID:84068

Gene names  (primary ):SLC10A7

Gene names  (synonym ):C4orf13 P7

Gene names  (ORF ):PSEC0051

Length:340

Mass:37432

Sequence:MRLLERMRKDWFMVGIVLAIAGAKLEPSIGVNGGPLKPEITVSYIAVATIFFNSGLSLKTEELTSALVHLKLHLFIQIFTLAFFPATIWLFLQLLSITPINEWLLKGLQTVGCMPPPVSSAVILTKAVGGNEAAAIFNSAFGSFLGIVITPLLLLLFLGSSSSVPFTSIFSQLFMTVVVPLIIGQIVRRYIKDWLERKKPPFGAISSSVLLMIIYTTFCDTFSNPNIDLDKFSLVLILFIIFSIQLSFMLLTFIFSTRNNSGFTPADTVAIIFCSTHKSLTLGIPMLKIVFAGHEHLSLISVPLLIYHPAQILLGSVLVPTIKSWMVSRQKGVKLTRPTV

Tissue specificity:Widely expressed (PubMed:15932064, PubMed:17628207). Expressed at high levels in liver and at lower levels in prostate, placenta, kidney, heart, lung, thymus and spleen (PubMed:15932064, PubMed:17628207). Strongly expressed in testis and also detected in brain, ovary, colon and small intestine (PubMed:17628207). Weakly expressed in testis and not detected in brain, ovary, colon or small intestine (PubMed:15932064). Isoform 1: Expressed in liver, testis and placenta (PubMed:17628207). Isoform 4: Expressed in liver, testis and placenta (PubMed:17628207). {ECO:0000269|PubMed:15932064, ECO:0000269|PubMed:17628207}.

Induction:

Developmental stage:Detected in the heart and vertebrae in embryos at 8 weeks of gestation (Carnegie stage 16), and in the long-bone cartilage at 9 weeks (Carnegie stages 19). {ECO:0000269|PubMed:30082715}.

Protein families:Bile acid:sodium symporter (BASS) (TC 2.A.28) family


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