GRHL1_HUMAN   Q9NZI5


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UniProt:Q9NZI5

Recommended name:Grainyhead-like protein 1 homolog

EC number:

Alternative names:(Mammalian grainyhead) (NH32) (Transcription factor CP2-like 2) (Transcription factor LBP-32)

Cleaved into:

GeneID:29841

Gene names  (primary ):GRHL1

Gene names  (synonym ):LBP32 MGR TFCP2L2

Gene names  (ORF ):

Length:618

Mass:70113

Sequence:MTQEYDNKRPVLVLQNEALYPQRRSYTSEDEAWKSFLENPLTAATKAMMSINGDEDSAAALGLLYDYYKVPRERRSSTAKPEVEHPEPDHSKRNSIPIVTEQPLISAGENRVQVLKNVPFNIVLPHGNQLGIDKRGHLTAPDTTVTVSIATMPTHSIKTETQPHGFAVGIPPAVYHPEPTERVVVFDRNLNTDQFSSGAQAPNAQRRTPDSTFSETFKEGVQEVFFPSDLSLRMPGMNSEDYVFDSVSGNNFEYTLEASKSLRQKPGDSTMTYLNKGQFYPITLKEVSSSEGIHHPISKVRSVIMVVFAEDKSREDQLRHWKYWHSRQHTAKQRCIDIADYKESFNTISNIEEIAYNAISFTWDINDEAKVFISVNCLSTDFSSQKGVKGLPLNIQVDTYSYNNRSNKPVHRAYCQIKVFCDKGAERKIRDEERKQSKRKVSDVKVPLLPSHKRMDITVFKPFIDLDTQPVLFIPDVHFANLQRGTHVLPIASEELEGEGSVLKRGPYGTEDDFAVPPSTKLARIEEPKRVLLYVRKESEEVFDALMLKTPSLKGLMEAISDKYDVPHDKIGKIFKKCKKGILVNMDDNIVKHYSNEDTFQLQIEEAGGSYKLTLTEI

Tissue specificity:Isoform 1 is highly expressed in brain, pancreas, tonsil, placenta and kidney. Isoform 2 is highly expressed in brain and liver. Expressed at very low levels in non-steroidogenic cells. {ECO:0000269|PubMed:10644752, ECO:0000269|PubMed:12175488}.

Induction:

Developmental stage:Expressed in fetal liver and brain. {ECO:0000269|PubMed:12175488}.

Protein families:Grh/CP2 family, Grainyhead subfamily


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