DEPP1_HUMAN   Q9NTK1


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UniProt:Q9NTK1

Recommended name:Protein DEPP1

EC number:

Alternative names:(Decidual protein induced by progesterone) (Fasting-induced gene protein) (FIG)

Cleaved into:

GeneID:11067

Gene names  (primary ):DEPP1

Gene names  (synonym ):C10orf10 DEPP FIG

Gene names  (ORF ):

Length:212

Mass:23406

Sequence:MRSRLLLSVAHLPTIRETTEEMLLGGPGQEPPPSPSLDDYVRSISRLAQPTSVLDKATAQGQPRPPHRPAQACRKGRPAVSLRDITARFSGQQPTLPMADTVDPLDWLFGESQEKQPSQRDLPRRTGPSAGLWGPHRQMDSSKPMGAPRGRLCEARMPGHSLARPPQDGQQSSDLRSWTFGQSAQAMASRHRPRPSSVLRTLYSHLPVIHEL

Tissue specificity:Expressed in various tissues, including pancreas, placenta, ovary, testis and kidney. {ECO:0000269|PubMed:16123073}.

Induction:By progesterone, testosterone and, to a much lower extent, estrogen. Induced by oxidative stress via FOXO3 activation (PubMed:28545464). Up-regulated by hypoxia (at protein level). {ECO:0000269|PubMed:16123073, ECO:0000269|PubMed:21510935, ECO:0000269|PubMed:28545464}.

Developmental stage:High levels in first trimester deciduas. Higher levels in the endometria during secretory phase than the proliferative phase, especially after the mid-secretory phase. {ECO:0000269|PubMed:16123073}.

Protein families:


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