KC1D_HUMAN P48730
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UniProt:P48730
Recommended name:Casein kinase I isoform delta
EC number:EC:2.7.11.1
Alternative names:(CKI-delta) (CKId) (Tau-protein kinase CSNK1D)
Cleaved into:
GeneID:1453
Gene names (primary ):CSNK1D
Gene names (synonym ):HCKID
Gene names (ORF ):
Length:415
Mass:47330
Sequence:MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRAADDAERERRDREERLRHSRNPATRGLPSTASGRLRGTQEVAPPTPLTPTSHTANTSPRPVSGMERERKVSMRLHRGAPVNISSSDLTGRQDTSRMSTSQIPGRVASSGLQSVVHR
Tissue specificity:Expressed in all tissues examined, including brain, heart, lung, liver, pancreas, kidney, placenta and skeletal muscle. However, kinase activity is not uniform, with highest kinase activity in splenocytes. In blood, highly expressed in hemopoietic cells and mature granulocytes. Also found in monocytes and lymphocytes. {ECO:0000269|PubMed:15070676, ECO:0000269|PubMed:16027726}.
Induction:
Developmental stage:Highly present in extravillous trophoblast cells, which are present at the placenta implantation site and invade the decidua and decidual vessels. {ECO:0000269|PubMed:16027726}.
Protein families:Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily