PHB2_HUMAN Q99623
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UniProt:Q99623
Recommended name:Prohibitin-2
EC number:
Alternative names:(B-cell receptor-associated protein BAP37) (D-prohibitin) (Repressor of estrogen receptor activity)
Cleaved into:
GeneID:11331
Gene names (primary ):PHB2
Gene names (synonym ):BAP REA
Gene names (ORF ):
Length:299
Mass:33296
Sequence:MAQNLKDLAGRLPAGPRGMGTALKLLLGAGAVAYGVRESVFTVEGGHRAIFFNRIGGVQQDTILAEGLHFRIPWFQYPIIYDIRARPRKISSPTGSKDLQMVNISLRVLSRPNAQELPSMYQRLGLDYEERVLPSIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELTERAKDFSLILDDVAITELSFSREYTAAVEAKQVAQQEAQRAQFLVEKAKQEQRQKIVQAEGEAEAAKMLGEALSKNPGYIKLRKIRAAQNISKTIATSQNRIYLTADNLVLNLQDESFTRGSDSLIKGKK
Tissue specificity:
Induction:Expression increases approximately 3-fold upon entry into G1 phase compared to other phases of the cell cycle. Also induced following inhibition of mitochondrial protein synthesis by thiamphenicol. {ECO:0000269|PubMed:11302691}.
Developmental stage:Levels of expression in fibroblasts decrease heterogeneously during cellular aging. {ECO:0000269|PubMed:11302691}.
Protein families:Prohibitin family