PHB2_HUMAN   Q99623


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UniProt:Q99623

Recommended name:Prohibitin-2

EC number:

Alternative names:(B-cell receptor-associated protein BAP37) (D-prohibitin) (Repressor of estrogen receptor activity)

Cleaved into:

GeneID:11331

Gene names  (primary ):PHB2

Gene names  (synonym ):BAP REA

Gene names  (ORF ):

Length:299

Mass:33296

Sequence:MAQNLKDLAGRLPAGPRGMGTALKLLLGAGAVAYGVRESVFTVEGGHRAIFFNRIGGVQQDTILAEGLHFRIPWFQYPIIYDIRARPRKISSPTGSKDLQMVNISLRVLSRPNAQELPSMYQRLGLDYEERVLPSIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELTERAKDFSLILDDVAITELSFSREYTAAVEAKQVAQQEAQRAQFLVEKAKQEQRQKIVQAEGEAEAAKMLGEALSKNPGYIKLRKIRAAQNISKTIATSQNRIYLTADNLVLNLQDESFTRGSDSLIKGKK

Tissue specificity:

Induction:Expression increases approximately 3-fold upon entry into G1 phase compared to other phases of the cell cycle. Also induced following inhibition of mitochondrial protein synthesis by thiamphenicol. {ECO:0000269|PubMed:11302691}.

Developmental stage:Levels of expression in fibroblasts decrease heterogeneously during cellular aging. {ECO:0000269|PubMed:11302691}.

Protein families:Prohibitin family


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