PXL2B_MOUSE Q9DB60
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UniProt:Q9DB60
Recommended name:Prostamide/prostaglandin F synthase
EC number:EC 1.11.1.20
Alternative names:(Prostamide/PG F synthase) (Prostamide/PGF synthase) (Peroxiredoxin-like 2B)
Cleaved into:
GeneID:66469
Gene names (primary ):Prxl2b
Gene names (synonym ):Fam213b
Gene names (ORF ):
Length:201
Mass:21670
Sequence:MNVVDLGRVGACVLKHAVTGEAVELRSLWQEKACVVAGLRRFGCMVCRWIAQDLSNLRSILDQHDVRLVGVGPEALGLQEFLDGGYFSGELYLDESKQIYKELGFKRYNSLSILPAALGKPVRDVASKAKAVGIQGNLSGDLLQSGGLLVVSKGGDKVLLHFIQKSPGDYVPQENILQALGISAEVCSSKPPQCDEEVCGR
Tissue specificity:Mainly present in brain and spinal cord. In spinal cord, present in the superficial layer of the dorsal horn, in motor neurons of the ventral horn and in glia of the white matter of the spinal cord. In brain, expressed preferentially in the white matter bundles of the entire CNS of adult with less marked expression in neuronal cell bodies. Colocalizes with MBP in myelin sheaths but not in axons. Localizes to myelin sheaths (at protein level). {ECO:0000269|PubMed:18006499, ECO:0000269|PubMed:20950588}.
Induction:
Developmental stage:
Protein families:Peroxiredoxin-like PRXL2 family, Prostamide/prostaglandin F synthase subfamily