PXL2B_MOUSE   Q9DB60


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UniProt:Q9DB60

Recommended name:Prostamide/prostaglandin F synthase

EC number:EC 1.11.1.20

Alternative names:(Prostamide/PG F synthase) (Prostamide/PGF synthase) (Peroxiredoxin-like 2B)

Cleaved into:

GeneID:66469

Gene names  (primary ):Prxl2b

Gene names  (synonym ):Fam213b

Gene names  (ORF ):

Length:201

Mass:21670

Sequence:MNVVDLGRVGACVLKHAVTGEAVELRSLWQEKACVVAGLRRFGCMVCRWIAQDLSNLRSILDQHDVRLVGVGPEALGLQEFLDGGYFSGELYLDESKQIYKELGFKRYNSLSILPAALGKPVRDVASKAKAVGIQGNLSGDLLQSGGLLVVSKGGDKVLLHFIQKSPGDYVPQENILQALGISAEVCSSKPPQCDEEVCGR

Tissue specificity:Mainly present in brain and spinal cord. In spinal cord, present in the superficial layer of the dorsal horn, in motor neurons of the ventral horn and in glia of the white matter of the spinal cord. In brain, expressed preferentially in the white matter bundles of the entire CNS of adult with less marked expression in neuronal cell bodies. Colocalizes with MBP in myelin sheaths but not in axons. Localizes to myelin sheaths (at protein level). {ECO:0000269|PubMed:18006499, ECO:0000269|PubMed:20950588}.

Induction:

Developmental stage:

Protein families:Peroxiredoxin-like PRXL2 family, Prostamide/prostaglandin F synthase subfamily


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