MTA70_MOUSE Q8C3P7
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UniProt:Q8C3P7
Recommended name:N6-adenosine-methyltransferase subunit METTL3
EC number:EC 2.1.1.348
Alternative names:(Methyltransferase-like protein 3) (N6-adenosine-methyltransferase 70 kDa subunit) (MT-A70)
Cleaved into:
GeneID:56335
Gene names (primary ):Mettl3
Gene names (synonym ):Mta70
Gene names (ORF ):
Length:580
Mass:64616
Sequence:MSDTWSSIQAHKKQLDSLRERLQRRRKQDSGHLDLRNPEAALSPTFRSDSPVPTAPTSSGPKPSTTSVAPELATDPELEKKLLHHLSDLALTLPTDAVSIRLAISTPDAPATQDGVESLLQKFAAQELIEVKRGLLQDDAHPTLVTYADHSKLSAMMGAVADKKGLGEVAGTIAGQKRRAEQDLTTVTTFASSLASGLASSASEPAKEPAKKSRKHAASDVDLEIESLLNQQSTKEQQSKKVSQEILELLNTTTAKEQSIVEKFRSRGRAQVQEFCDYGTKEECMKASDADRPCRKLHFRRIINKHTDESLGDCSFLNTCFHMDTCKYVHYEIDACVDSESPGSKEHMPSQELALTQSVGGDSSADRLFPPQWICCDIRYLDVSILGKFAVVMADPPWDIHMELPYGTLTDDEMRRLNIPVLQDDGFLFLWVTGRAMELGRECLNLWGYERVDEIIWVKTNQLQRIIRTGRTGHWLNHGKEHCLVGVKGNPQGFNQGLDCDVIVAEVRSTSHKPDEIYGMIERLSPGTRKIELFGRPHNVQPNWITLGNQLDGIHLLDPDVVARFKQRYPDGIISKPKNL
Tissue specificity:Present in both germ cells and somatic cells during testis development (at protein level) (PubMed:28809392). {ECO:0000269|PubMed:28809392, ECO:0000269|PubMed:28914256}.
Induction:
Developmental stage:
Protein families:MT-A70-like family