IL1AP_MOUSE Q61730
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UniProt:Q61730
Recommended name:Interleukin-1 receptor accessory protein
EC number:EC 3.2.2.6
Alternative names:(IL-1 receptor accessory protein) (IL-1RAcP) (Interleukin-33 receptot beta chain)
Cleaved into:
GeneID:16180
Gene names (primary ):Il1rap
Gene names (synonym ):
Gene names (ORF ):
Length:570
Mass:65741
Sequence:MGLLWYLMSLSFYGILQSHASERCDDWGLDTMRQIQVFEDEPARIKCPLFEHFLKYNYSTAHSSGLTLIWYWTRQDRDLEEPINFRLPENRISKEKDVLWFRPTLLNDTGNYTCMLRNTTYCSKVAFPLEVVQKDSCFNSAMRFPVHKMYIEHGIHKITCPNVDGYFPSSVKPSVTWYKGCTEIVDFHNVLPEGMNLSFFIPLVSNNGNYTCVVTYPENGRLFHLTRTVTVKVVGSPKDALPPQIYSPNDRVVYEKEPGEELVIPCKVYFSFIMDSHNEVWWTIDGKKPDDVTVDITINESVSYSSTEDETRTQILSIKKVTPEDLRRNYVCHARNTKGEAEQAAKVKQKVIPPRYTVELACGFGATVFLVVVLIVVYHVYWLEMVLFYRAHFGTDETILDGKEYDIYVSYARNVEEEEFVLLTLRGVLENEFGYKLCIFDRDSLPGGIVTDETLSFIQKSRRLLVVLSPNYVLQGTQALLELKAGLENMASRGNINVILVQYKAVKDMKVKELKRAKTVLTVIKWKGEKSKYPQGRFWKQLQVAMPVKKSPRWSSNDKQGLSYSSLKNV
Tissue specificity:Detected in lung, brain, spleen, thymus and liver. Expressed in brain endothelial cells, astrocytes, microglia and neurons. Isoform 3 is predominantly expressed in brain; expressed in hippocampal neurons. {ECO:0000269|PubMed:19481478, ECO:0000269|PubMed:21349253, ECO:0000269|PubMed:22159118, ECO:0000269|PubMed:7775431}.
Induction:
Developmental stage:
Protein families:Interleukin-1 receptor family