FOG2_MOUSE Q8CCH7
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UniProt:Q8CCH7
Recommended name:Zinc finger protein ZFPM2
EC number:
Alternative names:(Friend of GATA protein 2) (FOG-2) (Friend of GATA 2) (mFOG-2) (Zinc finger protein multitype 2)
Cleaved into:
GeneID:22762
Gene names (primary ):Zfpm2
Gene names (synonym ):Fog2
Gene names (ORF ):
Length:1151
Mass:127692
Sequence:MSRRKQSKPRQIKRPLEDAIDDEEEECPVEEAEVISKGDFPLEGSFPAGFEPENLSCEDVEFFCNKGDDEGIQEPAESDGDSHSDKPGQPGVETDDWDGPGELEVFQRDGERKIQSRQQLPVGTTWGPFAGKMDLNNNSLKTKAQVPMVLTAGPKWLLDVTWQGVEDSKNNCIVYSKGGQLWCTTTKAISEGEELVAFVVDFDSRLQAASHMTLTEGMYPARLLDSIQLLPQQAAMASILPTAIVNKDIFPCKSCGIWYRSERNLQAHLMYYCSGRQREAAPVSEENEDNSHQVSSLCPFPQCTKSFSNARALEMHLNSHSGVKMEEFLPPGASLKCTVCSYTADSVINFHQHLFSHLTQAAFRCNHCHFGFQTQRELLQHQELHVPSGKLPRESDMEHSPSGTEDSLQPATDLLARSDLSQSQKAMPTKDASSDTELDKCEKKTQLFLTNQRPEIQPAANKQNFSYTKIKSEPSSPRLASSPVQPNIGPSFPVGPFLSQFAFPQDITMVPQASEILAKMSELVHRRLRHGSSSYPPVIYSPLMPKGATCFECNITFNNLDNYLVHKKHYCSSRWQQMAKSPEFPSVSEKMPEAVSPNTGQTSINLLNPAAHSSDPENPLLQTSCINSSTVLDLIGPNGKGHEKDFSTQVKKLPTSNSSDDKINGKPVDVKNPSGPLVDGESDPNKTTCEACNITFSRHETYMVHKQYYCATRHDPPLKRSASNKVPAMQRTMRTRKRRKMYEMCLPEQEQRPPLVQQRFLDVANLSNPCSSTQEPTEGLGECYHPRCDIFPGIVSKHLETSLAMNKCVPVPKCDTTHSNVSCLEMDVPIDLSKKCLSQSERTTASPKRLLDYHECTVCKISFNKVENYLAHKQNFCPVTAHQRNDLGQLDGKVFPNPESERSSPEVSFERNMIKCEKNGNPKQPSPNGNLFSSHLATLQGLKVFSEAAQLIATKEENKHLFLPQCLYPGAIKKTKGADQLSPYYGIKPSDYIASSLVIHNTDVEQSTNTENESPKGQASSNGCAVPKKDSLPLLPKNRGMVIVNGGLKQDERPTANPQQENISQNTQHEDGHKSPSWISENPLAANENVSPGIPCAEEQLSSIAKGVNGASQAPSSGKYCRLCDIQFNNLSNFITHKKFYCSSHAAEHVK
Tissue specificity:Expressed in heart, brain and testis. Weakly expressed in lung and liver. First expressed at approximately E8.5 in the developing ventral heart tube and septum transversum. Cardiac expression persists throughout the remainder of embryonic development in the atria as well as in all layers of the ventricles (endocardium, myocardium, and pericardium). Expressed in the neuroepithelium of the developing midbrain and hindbrain from E11.5 and increased in intensity between E12 and E16.5. Also expressed in the urogenital ridge beginning at E11.5 and subsequently localized to the gonads by E16.5. Colocalizes with GATA4 GATA5 and GATA6 in the developing heart, GATA3 in the brain, and GATA4 in the gonads. {ECO:0000269|PubMed:10330188, ECO:0000269|PubMed:9927674, ECO:0000269|PubMed:9927675}.
Induction:
Developmental stage:
Protein families:FOG (Friend of GATA) family