NLS1_MOUSE Q9DA75
We list detailed information on various proteins on this webpage, which EnkiLife references when developing protein-related products. The protein data is sourced from UniProt, and since UniProt updates its information periodically, the data on our webpage may not always be up-to-date or may contain inaccuracies. If you notice any errors while browsing, we warmly welcome your feedback. Additionally, if you have any suggestions regarding any aspect of our website, please feel free to share them with us. As a token of our appreciation, we will offer a free product or a discount voucher for purchases to scientists who provide feedback. Please contact us at Email: order@enkilife.com; to share your feedback and get your rewards.
UniProt:Q9DA75
Recommended name：Sodium-dependent lysophosphatidylcholine symporter 1
EC number：
Alternative names：(NLS1) (Sodium-dependent LPC symporter 1) (Major facilitator superfamily domain-containing protein 2A)
Cleaved into：
GeneID：76574
Gene names (primary )：Mfsd2a
Gene names (synonym )：Mfsd2 Nls1
Gene names (ORF )：
Length：534
Mass：58984
Sequence：MAKGEGAESGSAAGLLPTSILQASERPVQVKKEPKKKQQLSICNKLCYAVGGAPYQLTGCALGFFLQIYLLDVAKVEPLPASIILFVGRAWDAFTDPLVGFCISKSSWTRLGRLMPWIIFSTPLAIIAYFLIWFVPDFPSGTESSHGFLWYLLFYCLFETLVTCFHVPYSALTMFISTEQSERDSATAYRMTVEVLGTVIGTAIQGQIVGQAKAPCLQDQNGSVVVSEVANRTQSTASLKDTQNAYLLAAGIIASIYVLCAFILILGVREQRELYESQQAESMPFFQGLRLVMGHGPYVKLIAGFLFTSLAFMLVEGNFALFCTYTLDFRNEFQNLLLAIMLSATFTIPIWQWFLTRFGKKTAVYIGISSAVPFLILVALMERNLIVTYVVAVAAGVSVAAAFLLPWSMLPDVIDDFHLKHPHSPGTEPIFFSFYVFFTKFASGVSLGVSTLSLDFANYQRQGCSQPEQVKFTLKMLVTMAPIILILLGLLLFKLYPIDEEKRRQNKKALQALREEASSSGCSDTDSTELASIL
Tissue specificity：Widely expressed. Exhibits an oscillatory pattern of expression in brown adipose tissue and liver consistent with a circadian rhythm. Enriched in brain micro-vessels, where it is specifically present in endothelium constituting the blood-brain barrier (at protein level) (PubMed:24828044, PubMed:24828040). {ECO:0000269|PubMed:18694395, ECO:0000269|PubMed:23209793, ECO:0000269|PubMed:24828040, ECO:0000269|PubMed:24828044}.
Induction：By fasting in liver and brown adipose tissue as well as by cold exposure in brown adipose tissue. Expression following fasting is dependent on glucagon signaling and Ppara. {ECO:0000269|PubMed:18694395, ECO:0000269|PubMed:23209793}.
Developmental stage：
Protein families：Major facilitator superfamily