COA8_MOUSE Q9CQW7
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UniProt:Q9CQW7
Recommended name：Cytochrome c oxidase assembly factor 8
EC number：
Alternative names：(COA8) (Apoptogenic protein 1, mitochondrial) (APOP-1)
Cleaved into：
GeneID：68020
Gene names (primary )：Coa8
Gene names (synonym )：Apop1 Apopt1
Gene names (ORF )：
Length：192
Mass：22715
Sequence：MAALRPGSRALRRLLCRSFSGGGGVRLARERPTDHRDAASSRVSRFCPPRQSCHDWIGPPDKCSNLRPVHFHIPENESPLEQRLRELRQETQEWNQQFWAKQNLSFNKEKEEFIYSRLQAKGAGLRTESGQRATLDAEEMADFYKDFLSKNFQKHMRYNRDWYKRNFAITFFMGKVVLERMWSKLRQKKTSS
Tissue specificity：Expressed in atherosclerotic smooth muscle cells (at protein level). Expressed in aorta, brain, heart, kidney, liver, lung and spleen. Isoform 1 is strongly expressed in Kidney. Isoform 2 is strongly expressed in brain. {ECO:0000269|PubMed:16782708}.
Induction：In conditions of increased oxidative stress, the protein is stabilized, increasing its mature intramitochondrial form and thereby protecting COX from oxidatively induced degradation. {ECO:0000269|PubMed:30552096}.
Developmental stage：
Protein families：COA8 family