PIM2_MOUSE Q62070
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UniProt:Q62070
Recommended name:Serine/threonine-protein kinase pim-2
EC number:EC 2.7.11.1
Alternative names:
Cleaved into:
GeneID:18715
Gene names (primary ):Pim2
Gene names (synonym ):Pim-2
Gene names (ORF ):
Length:370
Mass:40060
Sequence:MARATNLNAAPSAGASGPPDSLPSTLAPPSPGSPAALPRASTPCGLSGFSGLNIRSTSSMLTKPLQGHPSPPVTPTQPPGGKDRAAFEAEYRLGPLLGKGGFGTVFAGHRVTDRRQVAIKVISRNRVLGWSTVSDSVTCPLEVALLWKVGEGNGHPGVIRLLDWFETPEGFMLVLERPMPAQDLFDYITEKGPLGESCSRSFFTQVVAAVQHCHARGVVHRDIKDENILIDLCRGSIKLIDFGSGALLHDEPYTDFDGTRVYSPPEWISRHQYHALPATVWSLGVLLYDMVCGDIPFERDQEILEAELHFPAHVSPDCCALIRRCLAPKPCSRPSLEEILLDPWMQSPAEEKPINSSKGSPTPLPWSLLP
Tissue specificity:Widely expressed, with highest expression in spleen, thymus and brain. Expressed in epiphyseal chondrocytes. {ECO:0000269|PubMed:17476689, ECO:0000269|PubMed:9294606}.
Induction:Induced by a wide range of growth factors and mitogens; IL2, IL3, IL4, IL7,IL9 and by interferon-gamma (IFNG). {ECO:0000269|PubMed:12954615, ECO:0000269|PubMed:15642745, ECO:0000269|PubMed:9294606}.
Developmental stage:
Protein families:Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamily