KRT84_MOUSE Q99M73
We list detailed information on various proteins on this webpage, which EnkiLife references when developing protein-related products. The protein data is sourced from UniProt, and since UniProt updates its information periodically, the data on our webpage may not always be up-to-date or may contain inaccuracies. If you notice any errors while browsing, we warmly welcome your feedback. Additionally, if you have any suggestions regarding any aspect of our website, please feel free to share them with us. As a token of our appreciation, we will offer a free product or a discount voucher for purchases to scientists who provide feedback. Please contact us at Email: order@enkilife.com; to share your feedback and get your rewards.
UniProt:Q99M73
Recommended name：Keratin, type II cuticular Hb4
EC number：
Alternative names：(65 kDa type II keratin) (Keratin-84) (K84) (Type II hair keratin Hb4) (Type-II keratin Kb24)
Cleaved into：
GeneID：16680
Gene names (primary )：Krt84
Gene names (synonym )：Krt2-16 Krthb4
Gene names (ORF )：
Length：603
Mass：64983
Sequence：MSCRSYRVSSGRRVGSFSSCSAMAPQHLNRFRSSSVSCRSGPGFRGLGGFGSRSVINFGSSSPRIAVGCSRPVRCGVGFGAGSGMAFGSGDGLGFRASSGVGLGFGAGGCPSYGFGGPGFGGPGFGGPGFGYRIGGIGGPSAPAITAVTVNQSLLTPLNLEIDPNAQRVKRDEKEQIKTLNNKFASFIDKVRFLEQQNKLLETKWSFLQEQKCARSNLEPLFDNYITNLRRQLDVLSSDQARLQAERNHLQDILEGFKKKYEEEVVFRANAENEFVALKKDVDAAFLNKSDLEANVDTLIQETEFLKALYHEEIEMLQSHISETSVIVKMDNSRDLNLDGIIAEVKAQYEEVARRSRADVESWYQTKYEEMRVTAGQHCDNLRSTRDEINELTRLIQRLKAEIEHTKAQCAKLEAAVAEAEQQGEAALNDAKCKLADLEGALQQAKQDMARQLREYQELMNVKLALDIEIVTYRRLLEGEEIRICEGVGPVNISVSSSRGGVLCGPELVSGSSLSHNGGVTFSTSSSIRATGGVLASSSLRAGGDLLSSGSRGGSVLVGDACAPSIPCALPTEGGFSSCSGGRGNRSSSVRFSSTTTSRRTRY
Tissue specificity：In skin, only expressed in the suprabasal cells of tail scale epidermis. Suprabasally expressed in stratified squamous epithelia and also in the posterior unit of the complex filiform papillae of tongue. Expressed in rare anatomical sites in which an orthokeratinized stratum corneum would be too soft and a hard keratinized structure would be too rigid to meet the functional requirement of the respective epithelia. {ECO:0000269|PubMed:1385239}.
Induction：mRNA synthesis is suppressed during retinoic acid-mediated orthokeratotic conversion of tail scale epidermis. {ECO:0000269|PubMed:1385239}.
Developmental stage：
Protein families：Intermediate filament family