CLC2I_MOUSE Q9WVF9
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UniProt:Q9WVF9
Recommended name:C-type lectin domain family 2 member I
EC number:
Alternative names:(C-type lectin-related protein DCL1) (C-type lectin-related protein G) (Clr-g) (Lymphoid-derived C-type lectin-1) (LCL-1) (Osteoclast inhibitory lectin-related protein 2) (Ocil-related protein 2)
Cleaved into:
GeneID:93675
Gene names (primary ):Clec2i
Gene names (synonym ):Clrg Dcl1 Ocilrp2
Gene names (ORF ):
Length:217
Mass:24671
Sequence:MPDCLETGEKLFVHNMNAQCVQKPEEGNGPLGTGGKIVQGKCFRIISTVSPVKLYCCYGVIMVLTVAVIALSVALSTKKTEQIIINKTYAACSKNWTGVGNKCFYFSGYPRNWTFAQAFCMAQEAQLARFDNEEELIFLKRFKGDFDCWIGLHRESSEHPWKWTNNTEYNNMNPILGVGRYAYLSSDRISSSRSYINRMWICSKLNNYNLHCQTPPV
Tissue specificity:Detected in osteoblasts, growth plate chondrocytes and skeletal muscle overlying the bone (at protein level). Detected in spleen, B-cells, dendritic cells, thymus, and in IL2-activated natural killer cells. {ECO:0000269|PubMed:11398965, ECO:0000269|PubMed:12374791, ECO:0000269|PubMed:15963483}.
Induction:Up-regulated in CD4(+) T-cells upon stimulation with CD3-ligands. Up-regulated in cultured calvarial osteoblasts by 1,25-dihydroxyvitamin D3. Constitutively expressed in cultured bone marrow cells during osteoclast formation. {ECO:0000269|PubMed:12374791, ECO:0000269|PubMed:15963483}.
Developmental stage:
Protein families: