CLC2I_MOUSE   Q9WVF9


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UniProt:Q9WVF9

Recommended name:C-type lectin domain family 2 member I

EC number:

Alternative names:(C-type lectin-related protein DCL1) (C-type lectin-related protein G) (Clr-g) (Lymphoid-derived C-type lectin-1) (LCL-1) (Osteoclast inhibitory lectin-related protein 2) (Ocil-related protein 2)

Cleaved into:

GeneID:93675

Gene names  (primary ):Clec2i

Gene names  (synonym ):Clrg Dcl1 Ocilrp2

Gene names  (ORF ):

Length:217

Mass:24671

Sequence:MPDCLETGEKLFVHNMNAQCVQKPEEGNGPLGTGGKIVQGKCFRIISTVSPVKLYCCYGVIMVLTVAVIALSVALSTKKTEQIIINKTYAACSKNWTGVGNKCFYFSGYPRNWTFAQAFCMAQEAQLARFDNEEELIFLKRFKGDFDCWIGLHRESSEHPWKWTNNTEYNNMNPILGVGRYAYLSSDRISSSRSYINRMWICSKLNNYNLHCQTPPV

Tissue specificity:Detected in osteoblasts, growth plate chondrocytes and skeletal muscle overlying the bone (at protein level). Detected in spleen, B-cells, dendritic cells, thymus, and in IL2-activated natural killer cells. {ECO:0000269|PubMed:11398965, ECO:0000269|PubMed:12374791, ECO:0000269|PubMed:15963483}.

Induction:Up-regulated in CD4(+) T-cells upon stimulation with CD3-ligands. Up-regulated in cultured calvarial osteoblasts by 1,25-dihydroxyvitamin D3. Constitutively expressed in cultured bone marrow cells during osteoclast formation. {ECO:0000269|PubMed:12374791, ECO:0000269|PubMed:15963483}.

Developmental stage:

Protein families:


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