SH22A_MOUSE Q9QXK9
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UniProt:Q9QXK9
Recommended name:SH2 domain-containing protein 2A
EC number:
Alternative names:(Lck-associated adapter protein) (Lad) (Rlk/Itk-binding protein) (Ribp)
Cleaved into:
GeneID:27371
Gene names (primary ):Sh2d2a
Gene names (synonym ):Lad Ribp
Gene names (ORF ):
Length:374
Mass:40953
Sequence:MEFCLAQPCPQGNHEATSSTFNTFQPMNLTQGRCQNLSCGSRPSMQVMKEQGVQLSPRTNHTVVSASAPGTAWVLGNADRAEEVPGKGDLSLQAETRAWVQKTQAHWLLLKTAPLWFHGFITRREAERLLQPQPLGCYLVRFSESAVTFVLSYRSQTCCRHFLLAQLGDGRHVVLGEDSAHAQLQDLLEHYTECPLSPYGEILTQPLARQTAEPAGLSLRADSDSGSKRQDPDTQLSLLLQQGQAQASGHTEKVWASQQKATSQASRPRPPIPAKPQLPPEVYTSPASRLHQAPPINPIYQEPDEPIAFYAMGRGSPGDAPSNIYAEVEGPSGTAPIGHPILRKCWSRPISRGQVREVQGKISSRSRAERGSPS
Tissue specificity:Expression limited to tissues of the immune system and, in particular, activated T-cells and natural killer cells. Expressed in the thymus, lymph node, and to a lesser extent, in the spleen and bone marrow. According to PubMed:10553045, also expressed in the lung.
Induction:Up-regulated substantially after T-cell activation.
Developmental stage:
Protein families: