TRIM8_MOUSE Q99PJ2
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UniProt:Q99PJ2
Recommended name：Probable E3 ubiquitin-protein ligase TRIM8
EC number：EC 2.3.2.27
Alternative names：(Glioblastoma-expressed RING finger protein) (RING finger protein 27) (RING-type E3 ubiquitin transferase TRIM8) (Tripartite motif-containing protein 8)
Cleaved into：
GeneID：93679
Gene names (primary )：Trim8
Gene names (synonym )：Gerp Rnf27
Gene names (ORF )：
Length：551
Mass：61602
Sequence：MAENWKNCFEEELICPICLHVFVEPVQLPCKHNFCRGCIGEAWAKDSGLVRCPECNQAYNQKPGLEKNLKLTNIVEKFNALHVEKPPTALHCVFCRRGPPLPAQKVCLRCEAPCCQSHVQTHLQQPSTARGHLLVEADDVRAWSCPQHNAYRLYHCEAEQVAVCQYCCYYSGAHQGHSVCDVEIRRNEIRKMLMKQQERLEEREQDIEDQLYKLESDKRLVEEKVSQLKEEVRLQYEKLHQLLDEDLRQTVEVLDKAQAKFCSENAAQALHLGERMQEAKKLLGSLQRLFDKTEDVGFMKNTKSVKILMDRTQTCTGSSLSPPKIGHLNSKLFLNEVAKKEKQLRKMLEGPFSTPVPFLQSVPLYPCGVNSSGAEKRKHSTAFPEASFLETSSGPVGGQYGAAGTASSEGQSGQPLGPCSSTQHLVALPGGTQPVHSSPVFPPSQYPNGSTTQQPMLPQYGGRKILVCSVDNCYCSSVANHGGHQPYPRSGHFPWTVPSQEYSHPLPPTPSVPQSLPGLAVRDWLDASQQPGHQDFYRVYGQPSTKHYVTS
Tissue specificity：High expression in heart, liver, and thymus. Expressed in embryonic CNS, kidney, lens and gut. {ECO:0000269|PubMed:11331580, ECO:0000269|PubMed:12163497}.
Induction：
Developmental stage：At 10.5 and 12.5 dpc, expressed in the central nervous system. At 14.5 dpc, expressed in the eye (lens and inner neural layer of the retina), in the primitive glomeruli of the developing kidney, in the villi of the gut and in the dorsal root ganglia.
Protein families：TRIM/RBCC family