HMGN5_MOUSE   Q9JL35


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UniProt:Q9JL35

Recommended name:High mobility group nucleosome-binding domain-containing protein 5

EC number:

Alternative names:(Nucleosome-binding protein 1) (Nucleosome-binding protein 45) (NBP-45) (Protein GARP45)

Cleaved into:

GeneID:50887

Gene names  (primary ):Hmgn5

Gene names  (synonym ):Garp45 Nsbp1

Gene names  (ORF ):

Length:406

Mass:45344

Sequence:MPKRKAAGDVSQEPKRRSARLSAMPVPFTPELKPKRASTSRKTKTTNVVEENKDASTIPIPETKPEDVKDECNMENAENGEAKIMEAPIPKMEAEEVKEQINEDTEEDGGEKKEAVAAEAKDDELKANIQDVEKDEDGKEHKDTGEEVEDGKIEEEGLNEKPGTAKSEDAEVSKDEEEKGDNEKGEDGKEEGDEKEEEKDDKEGDTGTEKEVKEQNKEAEEDDGKCKEEENKEVGKEGQPEEDGKEDLHEEVGKEDLHEEDGKEGQPEEDGKEIHHEEDGKEGQPEEDGKEYLHEEDGEEGQPKEDQKEGQPEEDGKEDQPEEDGKEGQCKEDGKEGHHEEGGKEDLHEEDGKEKDGGKEDRKEEGEQEVAVDEGSDENKVEAEEEGAENKDFKQDGEKEEPLSIV

Tissue specificity:Expressed in liver, spleen, lung, heart, kidney, muscle and brain (at protein level). Widely expressed with highest levels in submaxillary gland, thymus, kidney and liver and lowest levels in brain, lung, pancreas and eye. {ECO:0000269|PubMed:10692437, ECO:0000269|PubMed:19748358}.

Induction:

Developmental stage:At 7.5 dpc, expression is detected in the ectoplacental cone but not in embryonic tissues. By 9.5 dpc and 12.5 dpc, strongly expressed in the giant trophoblast, spongiotrophoblast and decidual cells of the placenta (at protein level). At 9.5 dpc and 11.5 dpc, weakly expressed in the developing embryo. {ECO:0000269|PubMed:19160411}.

Protein families:HMGN family


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