SPY4_MOUSE Q9WTP2
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UniProt:Q9WTP2
Recommended name:Protein sprouty homolog 4
EC number:
Alternative names:(Spry-4)
Cleaved into:
GeneID:24066
Gene names (primary ):Spry4
Gene names (synonym ):
Gene names (ORF ):
Length:300
Mass:32523
Sequence:MEPPVPQSSVPVNPSSVMVQPLLDSRAPHSRLQHPLTILPIDQMKTSHVENDYIDNPSLAPATGPKRPRGGPPELAPTPARCDQDITHHWISFSGRPSSVSSSSSTSSDQRLLDHMAPPPVAEQASPRAVRLQPKVVHCKPLDLKGPTAPPELDKHFLLCEACGKCKCKECASPRTLPSCWVCNQECLCSAQTLVNYGTCMCLVQGIFYHCTNEDDEGSCADHPCSCSGSNCCARWSFMGALSVVLPCLLCYLPATGCVKLAQRGYDRLRRPGCRCKHTNSVICKAASGDTKTSRSDKPF
Tissue specificity:Expressed in the embryo and adult tissues including heart, brain, lung, kidney, and skeletal muscle.
Induction:By FGF signaling.
Developmental stage:At 8 dpc expressed in the lateral plate mesoderm of the primitive streak. At 9.5 and 10.5 dpc expressed in the nasal placodes, maxillary and mandibular processes, posterior part of the hyoid arch and the progress zone of the limb buds and the presomitic mesoderm. At 11.5 dpc expressed in the dorso-lateral region of the somites (mostly in the myotome) and in the otic vesicle. At 11.5 and 12.5 dpc expressed in the distal lung mesenchyme, with a strong expression in the accessory lobe of the lung. {ECO:0000269|PubMed:10330503}.
Protein families:Sprouty family