CARM1_MOUSE Q9WVG6
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UniProt:Q9WVG6
Recommended name:Histone-arginine methyltransferase CARM1
EC number:EC 2.1.1.319
Alternative names:(Coactivator-associated arginine methyltransferase 1) (Protein arginine N-methyltransferase 4)
Cleaved into:
GeneID:59035
Gene names (primary ):Carm1
Gene names (synonym ):Prmt4
Gene names (ORF ):
Length:608
Mass:65854
Sequence:MAAAAATAVGPGAGSAGVAGPGGAGPCATVSVFPGARLLTIGDANGEIQRHAEQQALRLEVRAGPDAAGIALYSHEDVCVFKCSVSRETECSRVGRQSFIITLGCNSVLIQFATPHDFCSFYNILKTCRGHTLERSVFSERTEESSAVQYFQFYGYLSQQQNMMQDYVRTGTYQRAILQNHTDFKDKIVLDVGCGSGILSFFAAQAGARKIYAVEASTMAQHAEVLVKSNNLTDRIVVIPGKVEEVSLPEQVDIIISEPMGYMLFNERMLESYLHAKKYLKPSGNMFPTIGDVHLAPFTDEQLYMEQFTKANFWYQPSFHGVDLSALRGAAVDEYFRQPVVDTFDIRILMAKSVKYTVNFLEAKEGDLHRIEIPFKFHMLHSGLVHGLAFWFDVAFIGSIMTVWLSTAPTEPLTHWYQVRCLFQSPLFAKAGDTLSGTCLLIANKRQSYDISIVAQVDQTGSKSSNLLDLKNPFFRYTGTTPSPPPGSHYTSPSENMWNTGSTYNLSSGVAVAGMPTAYDLSSVIAGGSSVGHNNLIPLANTGIVNHTHSRMGSIMSTGIVQGSSGAQGGGGSSSAHYAVNNQFTMGGPAISMASPMSIPTNTMHYGS
Tissue specificity:Ubiquitously expressed. Within the brain, present in proliferating cells from lateral ventricular zone and dentate gyrus (at protein level). {ECO:0000269|PubMed:10381882, ECO:0000269|PubMed:16508003}.
Induction:
Developmental stage:At 9 dpc, expression is prominent in the neural tube and somites. {ECO:0000269|PubMed:11713257}.
Protein families:Class I-like SAM-binding methyltransferase superfamily, Protein arginine N-methyltransferase family