FOXJ2_MOUSE   Q9ES18


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UniProt:Q9ES18

Recommended name:Forkhead box protein J2

EC number:

Alternative names:(Fork head homologous X)

Cleaved into:

GeneID:60611

Gene names  (primary ):Foxj2

Gene names  (synonym ):Fhx

Gene names  (ORF ):

Length:565

Mass:61570

Sequence:MASDLESSLTSIDWLPQLTLRATIEKLGSASQAGPPGGARKCSPGSPTDPNATLSKDEAAVHQDGKPRYSYATLITYAINSSPAKKMTLSEIYRWICDNFPYYKNAGIGWKNSIRHNLSLNKCFRKVPRPRDDPGKGSYWTIDTCPDISRKRRHPPDDDLSQDSPEQEASKSPRGGVPGSGEASLSHEGTPQMSLQSPSSVANYSQGPGSVDGGAVAAGAPGQESTEGAPPLYNTNHDFKFSYSEINFQDLSWSFRNLYKSMLERSSSSQHGFSSLLGDMPPSNNYYVYQQQQQQQPPPQPQPPPQQPQPQQQQAPTQGPSNVGGAPPLHTPSPDGCTTPGGKQAGAEGYGPPTGMAMHPPPLQHGGYHPHQHHPHSHPAQQPPQPQAQSQASINSTGFAFPPDWCSNIDSLKESFKMVNRLNWSSIEQSQFSELMESLRQAEQRNWTLDQHHIANLCDSLNHFLTQTGHMPQQGGSHRPPAPSRITDSCALTSGKPEPSMNQVNSYGHPQASHLYPGPAPMYPISTQDSAGYNRPAHHMVPRPPVPPPGANEEITDDFDWDLIT

Tissue specificity:In embryos, both cell layers of the blastocyst: the trophectoderm (TE) and the inner cell mass (ICM) show expression. Expressed in adult brain, heart skeletal muscle, lung, kidney and gonads. Liver, small intestine, and spleen also show expression but at lower levels. In the testis, expressed from pachytene spermatocytes to round spermatids, but not in spermatogonia. In addition to the germ lineage, also expressed in Sertoli cells of the testis. In the ovary, only granulosa cells of the follicles show expression. In the brain, expressed in the piriform cortex, hippocampus, habenula and in the granula cell layer in the cerebellum. {ECO:0000269|PubMed:11025217, ECO:0000269|PubMed:16376864}.

Induction:

Developmental stage:Expressed both maternally and zygotically. Zygotic expression first begins in 8-cell stage embryos, with expression increasing in blastocysts. {ECO:0000269|PubMed:11025217}.

Protein families:


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