TCF21_MOUSE O35437
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UniProt:O35437
Recommended name：Transcription factor 21
EC number：
Alternative names：(TCF-21) (Capsulin) (Epicardin) (Podocyte-expressed 1) (Pod-1)
Cleaved into：
GeneID：21412
Gene names (primary )：Tcf21
Gene names (synonym )：Pod1
Gene names (ORF )：
Length：179
Mass：19681
Sequence：MSTGSLSDVEDLQEVEMLDCDSLKVDSNKEFGTSNESTEEGSNCENGSPQKGRGGLGKRRKAPTKKSPLSGVSQEGKQVQRNAANARERARMRVLSKAFSRLKTTLPWVPPDTKLSKLDTLRLASSYIAHLRQILANDKYENGYIHPVNLTWPFMVAGKPENDLKEVVTANRLCGTTAS
Tissue specificity：Expressed at high levels in lung, kidney, gut, heart, ovary and podocytes (visceral glomerular epithelial cells). Also found in spleen, large intestine, uterus, bladder and testis.
Induction：
Developmental stage：Expressed during embryogenesis specifically in mesodermally-derived cells that surround the epithelium of the developing gastrointestinal, genitourinary, respiratory systems and in spiral septum of the heart and in epicardial precursor cells fated to form the coronary arteries. Expression pattern is sex- and stage-dependent during gonadogenesis. At 13.5 dpc expressed at higher levels in testis than ovary. In 3-month old adults expression drastically decreased in testis while it increased in ovary showing an opposite sex-dependent pattern in adults compared with fetuses. Expression in other organs was similar between the adults and the fetal stage.
Protein families：