C295L_MOUSE Q497N6
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UniProt:Q497N6
Recommended name:CEP295 N-terminal-like protein
EC number:
Alternative names:(Differential display clone 8) (KIAA1731 N-terminal like protein)
Cleaved into:
GeneID:58251
Gene names (primary ):Cep295nl
Gene names (synonym ):Ddc8 Kiaa1731nl
Gene names (ORF ):
Length:533
Mass:61957
Sequence:MQRDTERAAQLSPSSEDEALVLRQKPLEMPAQEEDSTTLQQWKARQLQRLAEELKAEWQEARLQQVRQAERLYLSHLLDEAAERSMGNDPSVHEQNQRRTAKHTRAKERNRAAFREERGRREEHPRQHPKSRKKAPCSERRSSAKARGPASGEKGKRRRVSSSKDHDGYQGPRVTRRVGVAKLNPFFDGDTDCMEDVQKEFFREGRRPSAKGTHNLRDQSLQGKTTALTQPLLHGPTCKQEAAAQEPPSKYNKNLWHKEIESTFEELFNMNRKLKKHLNLHLEQRLKADQNPDEQQSYSEIRSETFGTPREERTEEVETAEESGSPTEVETTEMWSKVNLKQILSDSEYPRYQQIAKYPLKSESLVPVKAGTSREQDDLLSLSPESGQEPPKSPLLEDESLKPYLQKQADSVASWMALRQKQKAELEQRRQKALLELTEHPNMSLEIHYKAELEEERRARRRMRLALLKSNSTGICALPPDRNNLSLDNGLLDEDKQNQMIRDLQQQILEQNKLHQEFLEKARKRLQEFQKSF
Tissue specificity:Expressed in mature spermatozoa (at protein level). Detected in retina, lung and kidney. In brain, highly expressed in brain-stem, cerebral cortex and thalamus with lesser expression in cerebellum and hippocampus. {ECO:0000269|PubMed:16985004, ECO:0000269|PubMed:19706271}.
Induction:Expression is moderately up-regulated 2 days after intracranial injury and increases at 4 and 7 days post-injury. {ECO:0000269|PubMed:16985004}.
Developmental stage:Expressed during the postmeiotic stages of spermatogenesis. Detected at least at 14 dpc, the expression being enriched in kidney and small intestine. Within the nervous system, expression is prominent in the most superficial layers of the posterior cerebral cortex at 14 dpc and retina at 18 dpc. Expression is enriched in the posterior cerebral cortex at birth and declines at 7 days after birth. {ECO:0000269|PubMed:16985004, ECO:0000269|PubMed:19706271, ECO:0000269|PubMed:9237247}.
Protein families: