REC8_MOUSE   Q8C5S7


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UniProt:Q8C5S7

Recommended name:Meiotic recombination protein REC8 homolog

EC number:

Alternative names:(Cohesin Rec8p)

Cleaved into:

GeneID:56739

Gene names  (primary ):Rec8

Gene names  (synonym ):Mei8 Rec8L1

Gene names  (ORF ):

Length:591

Mass:67425

Sequence:MFYYPNVLQRHTGCFATIWLAATRGSRLVKREYLNVNVVKTCEEILNYVLVRVQPPVAGLPRPRFSLYLSAQLQIGVIRVYFQQCQYLVEDIQHILEHLHRAQLRIRIDMEEADLPSLLLPNCLAMMETLEDAPEPFFGKMSVDPRLPSPFDIPQIRHLLEAATPEKTRKETLPEATPDPRKPDRTLATVQSPEVITLQEAEPIRMLQIEGEQDLPEISRGDLELLIAEKDDAILLEERQRGRLLRQRRASLPLDESREEPRALEGAGLVSALSPPAPAQVEGIQEALPGQVFPPEVQKMTGWEPGALLTEVTPPQELRLPAPPSTEKRLPSLQRPLPRRHRRRQLLFWDKETQISREKFEEQLQTGAHCWEYPVAQPPKRMLTSPAELFRTPTLSGWLPPELLGLWTHCAQVPQRMLRQRPQLETEETVEEERAADEEERRKTEALSEIEVLREAQEPSGPLMLSSELSLEAAEDEKSRTSLIPPEWWAWSEEGQPEPPALPMLPELPEVPMEMPPRPELSSEAVLRAVALKLQANKELDFSSLVPPLSPRKLASRVFYLLLVLSTQKILLVEQQKPYGPLLIRPGPKFP

Tissue specificity:Expressed primarily in the gonads. In the testis, expressed in pachytene spermatocytes and in spermatids. Not expressed in spermatogonia or somatic cells. In the ovary, expressed only in oocytes. Low levels also detected in a number of somatic tissues including thymus, lung, liver, kidney and small intestine. {ECO:0000269|PubMed:10207075, ECO:0000269|PubMed:12130806, ECO:0000269|PubMed:12759374, ECO:0000269|PubMed:15935783}.

Induction:

Developmental stage:Expressed from 2 weeks postpartum (at protein level). {ECO:0000269|PubMed:12759374}.

Protein families:Rad21 family


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