DPH1_MOUSE   Q5NCQ5


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UniProt:Q5NCQ5

Recommended name:2-(3-amino-3-carboxypropyl)histidine synthase subunit 1

EC number:EC 2.5.1.108

Alternative names:(Diphthamide biosynthesis protein 1) (Diphtheria toxin resistance protein 1) (Ovarian cancer-associated gene 1 protein homolog) (S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 1)

Cleaved into:

GeneID:116905

Gene names  (primary ):Dph1

Gene names  (synonym ):Dph2l1 Ovca1

Gene names  (ORF ):

Length:438

Mass:48004

Sequence:MAALVVSETAEPGSRVGPGRGRISRGRLANQIPPEVLNNPQLQAAVQVLPSNYNFEIPKTIWRIQQAQAKKVALQMPEGLLLFACTIVDILERFTEAEVMVMGDVTYGACCVDDFTARALGVDFLVHYGHSCLVPMDTSVQDFRVLYVFVDIRIDTAHLLDSVRLTFTPGSSLALVSTIQFVSTLQAAAQELKADYHISVPQCKPLSPGEILGCTSPRLSKEVEAVVYLGDGRFHLESVMIANPNIPAYRYDPYGKVLSREYYDHQRMQATRQEAIAAARSAKSWGLILGTLGRQGSPKILEHLESQLRNLGLPFVRLLLSEIFPSKLSLLPEVDVWVQVACPRLSIDWGSAFPKPLLTPYEAAVALKDISWQQPYPMDFYSGSSLGPWTVNYGRDRAPRGLCQPASDKVQQGSRGGSPAPACESCNCADQKATSPAP

Tissue specificity:Strongly expressed in kidney and liver. Moderately expressed in brain, skin and testis. Weakly expressed in heart, lung, small intestine, spleen, stomach and thymus. {ECO:0000269|PubMed:11527402}.

Induction:

Developmental stage:Expressed in embryos from 8.5 to 10.5 dpc. Expressed in lung, stomach, brain, heart, kidney and gonads at 14.5 dpc. {ECO:0000269|PubMed:11527402}.

Protein families:DPH1/DPH2 family, DPH1 subfamily


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