DPH1_MOUSE Q5NCQ5
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UniProt:Q5NCQ5
Recommended name:2-(3-amino-3-carboxypropyl)histidine synthase subunit 1
EC number:EC 2.5.1.108
Alternative names:(Diphthamide biosynthesis protein 1) (Diphtheria toxin resistance protein 1) (Ovarian cancer-associated gene 1 protein homolog) (S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 1)
Cleaved into:
GeneID:116905
Gene names (primary ):Dph1
Gene names (synonym ):Dph2l1 Ovca1
Gene names (ORF ):
Length:438
Mass:48004
Sequence:MAALVVSETAEPGSRVGPGRGRISRGRLANQIPPEVLNNPQLQAAVQVLPSNYNFEIPKTIWRIQQAQAKKVALQMPEGLLLFACTIVDILERFTEAEVMVMGDVTYGACCVDDFTARALGVDFLVHYGHSCLVPMDTSVQDFRVLYVFVDIRIDTAHLLDSVRLTFTPGSSLALVSTIQFVSTLQAAAQELKADYHISVPQCKPLSPGEILGCTSPRLSKEVEAVVYLGDGRFHLESVMIANPNIPAYRYDPYGKVLSREYYDHQRMQATRQEAIAAARSAKSWGLILGTLGRQGSPKILEHLESQLRNLGLPFVRLLLSEIFPSKLSLLPEVDVWVQVACPRLSIDWGSAFPKPLLTPYEAAVALKDISWQQPYPMDFYSGSSLGPWTVNYGRDRAPRGLCQPASDKVQQGSRGGSPAPACESCNCADQKATSPAP
Tissue specificity:Strongly expressed in kidney and liver. Moderately expressed in brain, skin and testis. Weakly expressed in heart, lung, small intestine, spleen, stomach and thymus. {ECO:0000269|PubMed:11527402}.
Induction:
Developmental stage:Expressed in embryos from 8.5 to 10.5 dpc. Expressed in lung, stomach, brain, heart, kidney and gonads at 14.5 dpc. {ECO:0000269|PubMed:11527402}.
Protein families:DPH1/DPH2 family, DPH1 subfamily