MSRB3_MOUSE Q8BU85
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UniProt:Q8BU85
Recommended name：Methionine-R-sulfoxide reductase B3, mitochondrial
EC number：EC 1.8.4.12
Alternative names：(MsrB3) (EC 1.8.4.14)
Cleaved into：
GeneID：320183
Gene names (primary )：Msrb3
Gene names (synonym )：
Gene names (ORF )：
Length：253
Mass：26832
Sequence：MPPAAPSVARSREGGGIGQRRLVFPKSARRTLPCPIALCLGLCLAAAAATTTRASAAAFASAGDTTAMSAFNLLHLVTKSQPVAPRACGLPSGSCRDKKNCKVVFSQQELRKRLTPLQYHVTQEKGTESAFEGEYTHHKDPGIYKCVVCGTPLFKSETKFDSGSGWPAFHDVISSEAIEFTDDFSYGMHRVETSCSQCGAHLGHIFDDGPRPTGKRYCINSASLSFTPADSSEAEGSGIKESGSPAAADRAEL
Tissue specificity：Widely expressed. Detected in the sensory epithelia of the organ of Corti and vestibular end organs as early as P2 up to adulthood (at protein level). In the organ of Corti, present in inner and outer hair cells and, to a lesser extent, in supporting cells (at protein level). In hair cells, distributed throughout the cell body. Barely detectable level in stereocilia. Also observed in spiral ganglion neurons, but not in the stria vascularis. In the vestibular end organs, found throughout the sensory epithelium, but more intense expression in hair cells than in supporting cells (at protein level). In vestibular hair cells, present within cell bodies and to a lesser extent in kinocilia. Barely detectable in stereocilia. {ECO:0000269|PubMed:21185009}.
Induction：
Developmental stage：Expressed in temporal bones at 15 dpc through postnatal 30, levels decrease thereafter, but is still present in the inner ear at P180.
Protein families：MsrB Met sulfoxide reductase family