FEZF2_MOUSE Q9ESP5
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UniProt:Q9ESP5
Recommended name:Fez family zinc finger protein 2
EC number:
Alternative names:(Forebrain embryonic zinc finger-like protein 2) (Zinc finger protein 312) (Zinc finger protein Fez-like)
Cleaved into:
GeneID:54713
Gene names (primary ):Fezf2
Gene names (synonym ):Fez Fezl Zfp312
Gene names (ORF ):
Length:455
Mass:48931
Sequence:MASSASLETMVPPACPRAGASPATSKTLAFSIERIMAKTSEPRAPFEPRPAALEADSSQSKKLLNLCSPLPCMIPLQPLGYEVPSKTLLSYSEFWKSSLRAGGGGGGGSGGGAPVCGASGLCKTNCGVCCKAELGLAPSALPAGRVIKPQVINQAVGLPASGSLYYFNYLDSTAYPPSELLGGHLFPSGLLNAQAPTSLAAHPKLFLLENAKLASLAADKFPHPASYPHKERLHAPLEQVLKENSALTAERGGVKSHSKLPGGSTDSKPKNFTCEVCGKVFNAHYNLTRHMPVHTGARPFVCKVCGKGFRQASTLCRHKIIHTQEKPHKCNQCGKAFNRSSTLNTHIRIHAGYKPFVCEFCGKGFHQKGNYKNHKLTHSGEKQYKCTICNKAFHQVYNLTFHMHTHNDKKPFTCATCGKGFCRNFDLKKHVRKLHDSVGPTATPSAKDLARTVQS
Tissue specificity:Highly expressed in neocortical layer V, moderately expressed in layer VI. Expressed in subcortically projecting neurons. {ECO:0000269|PubMed:16157277, ECO:0000269|PubMed:16314561}.
Induction:
Developmental stage:Expressed in the olfactory epithelium, hypothalamus, ventrolateral pallium and prethalamus at mid-gestation. At 12.5 dpc, highly enriched in the postmigratory pyramidal neurons forming the cortical plate situated beneath the pial surface. At 13.5 dpc, expressed in the ventricular zone and subventricular zone at low levels, expression is much higher in the developing cortical plate, where postmitotic neurons are positioned. During late embryonic and early postnatal development, expression disappears from cortical progenitors and becomes restricted to the subplate and the prospective layer V and VI pyramidal neurons. {ECO:0000269|PubMed:16157277, ECO:0000269|PubMed:16314561, ECO:0000269|PubMed:16540508}.
Protein families:Krueppel C2H2-type zinc-finger protein family