GADL1_MOUSE Q80WP8
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UniProt:Q80WP8
Recommended name:Acidic amino acid decarboxylase GADL1
EC number:EC 4.1.1.11
Alternative names:(Aspartate 1-decarboxylase) (ADC) (Cysteine sulfinic acid decarboxylase) (CSADC) (Glutamate decarboxylase-like protein 1)
Cleaved into:
GeneID:73748
Gene names (primary ):Gadl1
Gene names (synonym ):
Gene names (ORF ):
Length:550
Mass:62519
Sequence:MSHARDDHQGASQGSQWLSQARTLVQEGTLFNFIRCLLLFQGDSGQKEMTPGKKIPIFVDGVVLNGPQTDVKAGEKFVEEACRLIMEEVVLKATDVNEKVCEWQPPEQLRQLLDLEMRDTGESQDKLLKLCQDVIHFSVKTNHPRFFNQLYAGLDYYSLAARIITEALNPSIYTYEVSPVFLLVEEAVLKKMIECVGWKEGDGIFNPGGSVSNMCAMNLARYRHCPDIKEKGLSGLPRLILFTSAECHYSMKKAASFLGIGTQNVYFVETDGRGKMIPEDLEKQIWQARQEGAVPFLVCATSGTTVLGAFDPLDEIAEVCERHGLWLHVDASWGGSALVSRKHRRLLHGIHRADSVAWNPHKMLMAGIQCSALLVKDKSDLLKKCYSAKATYLFQQDKFYDVSYDTGDKSIQCSRRPDAFKFWMTWKALGTSGLEERVNRAFALSRYLVDEIKKREGFKLLMEPEYTNVCFWYIPPSLREMEEGPEFWRKLSLVAPAIKEKMMKKGSLMLGYQPHRGKVNFFRQVVISPQVSREDMDFLLDEIDSLGRDM
Tissue specificity:Expressed in skeletal muscles and kidney (at protein level). Expressed in skeletal muscle and weakly in brain. Not expressed in liver or kidney. Expressed in brain, olfactory bulb, liver, muscle and kidney with the highest expression in olfactory bulb and almost not detected in liver (at protein level) (PubMed:26327310). {ECO:0000269|PubMed:23038267, ECO:0000269|PubMed:26327310}.
Induction:
Developmental stage:Expression in total brain lysate is weak but seems to decrease with age as detected from 17 dpc to 12 months. {ECO:0000269|PubMed:26327310}.
Protein families:Group II decarboxylase family