DACT1_MOUSE   Q8R4A3


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UniProt:Q8R4A3

Recommended name:Dapper homolog 1

EC number:

Alternative names:(Dapper antagonist of catenin 1) (Frodo homolog) (MDpr1) (Thymus-expressed novel gene 3 protein)

Cleaved into:

GeneID:59036

Gene names  (primary ):Dact1

Gene names  (synonym ):Thyex3

Gene names  (ORF ):

Length:778

Mass:84306

Sequence:MKPDAAREPEPLSPGRGAEAEGRWRERGEADTERQRTRERQEATLAGLAELGYLRQRQELLVRGALRCSGTVGTVAPRSGELRGDAAQRSRLEEKFLEENILLLRRQLNCLRRRDAGLLNQLQELDKQISDLRLDVEKTSEEHLETDSRPSSGFYELSDGASGSLSNSSNSVFSECLSSCHSSTCFCSPLEAALTISDGCPKSADVNPKYQCDLVSKNGNDVYRYPSPLHAVAVQSPMFLLCLTGNTLREEEGLGSHASDICIGSELNATKTDNSLPSPSSLWSASHPASSKKMDGYILSLVQKKTHPVRTNKPRTSVNADPTKGLLRNGSVCVRAPSGVPPGSSVNFKNTKQMCLPAGGITSLENGPFSPPKQRSKDSKTDQLESKRLALPESCSAGAAMEPQSKHVPKAAKAASQELTRCQAGLGESMKESNQASAVSPKTSPGRGPVAPAESKALQLPKKMSQKNSLQAVPALDRPALDFKSEGSSQSLEEGHLVKAQFIPGQQAAARPHRAHRNPGVARSATLKARGQAAMEHGLPTVREKPRAAGKKCRFPDDSDTNKKFRKTSAKGRRSGGLQDAGLPGRALGTGGHRAGSRAHAHGREPVVAKPKHKRTDYRRWKSSAEVSYEEALRRARRARREHGAAYRVAVALPYASPYAYVPSDSEYSAECESLFHSTVVDTSEDEQSNYTTNCFGDSESSVSEGDFVGESTTTSDSEESGGLIWSQFVQTLPIQTVTAPDLHTRPTKTFVKIKASHNLKKKILRFRSGSLKLMTTV

Tissue specificity:Expressed in multiple tissues including brain, heart, kidney, liver and testis. {ECO:0000269|PubMed:11970895, ECO:0000269|PubMed:16881060}.

Induction:

Developmental stage:Expression strongly increases from 9.5 dpc, peaks between 11.5 dpc and 13.5 dpc and diminishes slowly thereafter. Expressed in the somites during segmentation, limb bud mesenchyme, and developing central nervous system. Expressed in primitive streak mesoderm, neuroectoderm, neural crest, presomitic mesoderm and somites. {ECO:0000269|PubMed:16278878, ECO:0000269|PubMed:16881060}.

Protein families:Dapper family


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