PEDF_MOUSE P97298
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UniProt:P97298
Recommended name：Pigment epithelium-derived factor
EC number：
Alternative names：(PEDF) (Caspin) (Serpin F1) (Stromal cell-derived factor 3) (SDF-3)
Cleaved into：
GeneID：20317
Gene names (primary )：Serpinf1
Gene names (synonym )：Pedf Sdf3
Gene names (ORF )：
Length：417
Mass：46234
Sequence：MQALVLLLWTGALLGHGSSQNVPSSSEGSPVPDSTGEPVEEEDPFFKVPVNKLAAAVSNFGYDLYRLRSSASPTGNVLLSPLSVATALSALSLGAEHRTESVIHRALYYDLITNPDIHSTYKELLASVTAPEKNLKSASRIVFERKLRVKSSFVAPLEKSYGTRPRILTGNPRVDLQEINNWVQAQMKGKIARSTREMPSALSILLLGVAYFKGQWVTKFDSRKTTLQDFHLDEDRTVRVPMMSDPKAILRYGLDSDLNCKIAQLPLTGSMSIIFFLPLTVTQNLTMIEESLTSEFIHDIDRELKTIQAVLTVPKLKLSFEGELTKSLQDMKLQSLFESPDFSKITGKPVKLTQVEHRAAFEWNEEGAGSSPSPGLQPVRLTFPLDYHLNQPFLFVLRDTDTGALLFIGRILDPSST
Tissue specificity：Highly expressed in the liver, gastric glandular mucosa and renal tubules. It is also expressed in the brain, heart, lung retina and testes. {ECO:0000269|PubMed:9565647, ECO:0000269|PubMed:9614124}.
Induction：
Developmental stage：First detected at 12.5 dpc in cartilage primordium, it is present in the osseous matrix of developing limbs, vertebrae, ribs and skull. At 16.5 dpc it is detected in bone matrix and smooth muscle, and at lower levels in connective tissue, bronchial epithelial cells, metanephron microtubules, and skin. {ECO:0000269|PubMed:9614124}.
Protein families：Serpin family