TM108_MOUSE Q8BHE4
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UniProt:Q8BHE4
Recommended name:Transmembrane protein 108
EC number:
Alternative names:(Retrolinkin)
Cleaved into:
GeneID:81907
Gene names (primary ):Tmem108
Gene names (synonym ):
Gene names (ORF ):
Length:574
Mass:59642
Sequence:MKRSLQALYCQLLSFLLTLALTKALVLAVHEPSPRESLQTLPSGSPPGTMVTAPHSPTRLSSVLTLNPTPDGPSSQAAATLETTVSHPEGHPPTDTTSTVMGTAAVPHPESPLPTGSPPAAMTTTPSHSESLPPGDATPTTTLPTKPAGTTSRPTVAPRATTRRPPRPPGSSRKGAGGSTRTLTPVPGGHLARKESQRGRNQSSAHLGPKRPLGKIFQIYKGNFTGSAEPDPSALTPRTPLGGYFSSTQPQTVSPATAPRSTSRVPPTTSLVPVKDKPGFIRSNQGSGPILTSPGGEPAATAATGAPASTQPAPVPSQSPHGDVQDSASHSDSWLAVTPDTDRPTSASSGVFTAATGPTQAAFDATVSAPSPGIPQGPSATPQAPTRPSGVSESTVSPAEEEAEASPTTTDRGPRPLSTVLSTATGNFLNRLVPAGTWKPGTVANISHVAEGDKPQHRATICLSKMDIAWVIVAISVPISSCSVLLTVCCMRRKKKTANPENNLSYWNNAITMDYFNRHAVELPREIQSLETSEDQLSEPRSPANGDYRDTGMVLVNPFCQETLFVGNDQVSEI
Tissue specificity:Expressed in the nervous system tissues, such as hippocampus and spinal cord, is barely detectable in peripheral tissues such as heart, lung, liver, kidney and muscle (PubMed:17287360, PubMed:28096412). In brain, highly expressed in dentate gyrus neurons and expressed in cortex, olfactory bulb, ammon's horn, cerebellum, hypothalamus and striatum (PubMed:28096412, PubMed:21849472). {ECO:0000269|PubMed:17287360, ECO:0000269|PubMed:21849472, ECO:0000269|PubMed:28096412}.
Induction:
Developmental stage:In brain, detectable as early as 12 dpc and the level increases persistently through later embryonic stages to the adult age (PubMed:17287360). In the hippocampus, undetectable at postnatal day 1 (P1), detected at P7, the levels peak between P15 and P21 to remain at a high level during adulthood (PubMed:28096412). {ECO:0000269|PubMed:17287360, ECO:0000269|PubMed:28096412}.
Protein families: