TRAF3_MOUSE Q60803
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UniProt:Q60803
Recommended name：TNF receptor-associated factor 3
EC number：EC 2.3.2.27
Alternative names：(CD40 receptor-associated factor 1) (CRAF1) (RING-type E3 ubiquitin transferase TRAF3) (TRAFAMN)
Cleaved into：
GeneID：22031
Gene names (primary )：Traf3
Gene names (synonym )：Craf1 Trafamn
Gene names (ORF )：
Length：567
Mass：64294
Sequence：MESSKKMDAAGTLQPNPPLKLQPDRGAGSVLVPEQGGYKEKFVKTVEDKYKCEKCRLVLCNPKQTECGHRFCESCMAALLSSSSPKCTACQESIIKDKVFKDNCCKREILALQVYCRNEGRGCAEQLTLGHLLVHLKNECQFEELPCLRADCKEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIKLQKHEDTDCPCVVVSCPHKCSVQTLLRSELSAHLSECVNAPSTCSFKRYGCVFQGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRVTELESVDKSAGQAARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIVDTSDLPDP
Tissue specificity：Detected in bone marrow macrophages and spleen B-cells (at protein level). In adult, highest in brain. Also found in kidney, heart, thymus, spleen, lung, muscle, testis and ovary. Not found in liver. {ECO:0000269|PubMed:18997792, ECO:0000269|PubMed:19898473, ECO:0000269|PubMed:8660894}.
Induction：
Developmental stage：In the embryo, expressed from 6.5 dpc with highest levels found between 11.5 dpc and 13.5 dpc. At late stages of gestation, from 14.5 dpc, only low levels are detected.
Protein families：TNF receptor-associated factor family, A subfamily