DYR1B_MOUSE   Q9Z188


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UniProt:Q9Z188

Recommended name:Dual specificity tyrosine-phosphorylation-regulated kinase 1B

EC number:EC 2.7.12.1

Alternative names:

Cleaved into:

GeneID:13549

Gene names  (primary ):Dyrk1b

Gene names  (synonym ):

Gene names  (ORF ):

Length:629

Mass:69178

Sequence:MAVPPGHGPFSGFPGPQEHTQVLPDVRLLPRRLPLAFRDAASAPLRKLSVDLIKTYKHINEVYYAKKKRRAQQAPPQDSSTKKEKKVLNHGYDDDNHDYIVRSGERWLERYEIDSLIGKGSFGQVVKAYDHQTQELVAIKIIKNKKAFLNQAQIELRLLELMNQHDTEMKYYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGVSLNLTRKLAQQLCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGTPYDLAIDMWSLGCILVEMHTGEPLFSGSNEVDQMSRIVEVLGIPPAPMLEQAPKARKYFERLPGGGWTLRRTKELRKDYQGPGTRRLQEVLGVQTGGPGGRRAGEPGHSPADYLRFQDLVLRMLEYEPAARISPLGALQHGFFRRTADEATNTGPAGSSASTSPAPLDTCPSSSTASSISSSGGSSGSSNDNRAYRYSNRYCGGPGPPITDCEMNSPQVLPSQPLRPWAGGDVPHKTHQAPISASTLPGTGAQLPPLPRCLGRPPSPTSPPPPELMDVSLVGSPPDCSPPPPAPAPQHPAASALRTRMTGGRPPLPPPDDPATLGPRLGLHGVPQSTAASS

Tissue specificity:Isoform 1 and isoform 2 are broadly expressed. Isoform 3 seems specific for skeletal muscle (at protein level). {ECO:0000269|PubMed:12633499}.

Induction:

Developmental stage:Isoform 1 is present from 14 dpc. Isoform 3 is present from 18 dpc (at protein level). {ECO:0000269|PubMed:12633499}.

Protein families:Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamily


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