GIMA5_MOUSE Q8BWF2
We list detailed information on various proteins on this webpage, which EnkiLife references when developing protein-related products. The protein data is sourced from UniProt, and since UniProt updates its information periodically, the data on our webpage may not always be up-to-date or may contain inaccuracies. If you notice any errors while browsing, we warmly welcome your feedback. Additionally, if you have any suggestions regarding any aspect of our website, please feel free to share them with us. As a token of our appreciation, we will offer a free product or a discount voucher for purchases to scientists who provide feedback. Please contact us at Email: order@enkilife.com; to share your feedback and get your rewards.
UniProt:Q8BWF2
Recommended name：GTPase IMAP family member 5
EC number：
Alternative names：(GTPase of the immunity-associated protein 5) (Immunity-associated nucleotide 4-like 1 protein) (Immunity-associated protein 3)
Cleaved into：
GeneID：317757
Gene names (primary )：Gimap5
Gene names (synonym )：Ian4l1 Ian5 Imap3
Gene names (ORF )：
Length：308
Mass：34653
Sequence：MEHLQKSTYGTIVQGPEAHCVQESSCLRILLVGKSGCGKSATGNSILRRPAFQSRLRGQSVTRTSQAETGTWEGRSILVVDTPPIFESKAQNQDMDKDIGDCYLLCAPGPHVLLLVTQLGRFTAEDAMAVRMVKEVFGVGVMRHMIVLFTRKEDLEEKSLEEFVTHTDNRSLRSLTQECGRRYCAFNNRASGEEQQGQLAELMALVRRLEQECEGSFHSNDLFLHAEALLREGYSVHQEAYRCYLAKVRQEVEKQRRELEEQEGSWIAKMICTVKSCWSSHTAACALLIVLGLTLLTTFINLCISRCK
Tissue specificity：Expressed in thymus (in thymocytes), spleen (in splenocytes), lymph node and lung (PubMed:16509771). Highly expressed in T lymphocytes (PubMed:16509771, PubMed:21502331). Expressed in B cells and in distinct lineages of hematopoietic bone marrow cells, including natural killer, B, T, myeloid and erythroid lineages (PubMed:21502331). {ECO:0000269|PubMed:16509771, ECO:0000269|PubMed:21502331}.
Induction：
Developmental stage：Up-regulated upon the maturation of CD4/CD8 double-positive to CD4 single-positive thymocytes. {ECO:0000269|PubMed:16509771}.
Protein families：TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily, AIG1/Toc34/Toc159-like paraseptin GTPase family, IAN subfamily