EPHA3_MOUSE P29319
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UniProt:P29319
Recommended name：Ephrin type-A receptor 3
EC number：EC 2.7.10.1
Alternative names：(EPH-like kinase 4) (EK4) (mEK4) (Tyrosine-protein kinase TYRO4) (Tyrosine-protein kinase receptor ETK1)
Cleaved into：
GeneID：
Gene names (primary )：Epha3
Gene names (synonym )：Etk1 Mek4 Tyro4
Gene names (ORF )：
Length：983
Mass：109955
Sequence：MDCHLSILVLLGCCVLSCSGELSPQPSNEVNLLDSKTIQGELGWISYPSHGWEEISGVDEHYTPIRTYQVCNVMDHSQNNWLRTNWVPRNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDDHGVKFREHQFTKIDTIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGACVALVSVRVYFKKCPFTVKNLAMFPDTVPMDSQSLVEVRGSCVNNSKEEDPPRMYCSTEGEWLVPIGKCTCNAGYEERGFICQACRPGFYKASDGAAKCAKCPPHSSTQEDGSMNCRCENNYFRAEKDPPSMACARPPSAPRNVISNINETSVILDWSWPLDTGGRKDITFNIICKKCGWNVRQCEPCSPNVRFLPRQLGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQYAAVSITTNQAAPSPVMTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYQKQEQETSYTILRARGTNVTISSLKPDTTYVFQIRARTAAGYGTNSRKFEFETSPDSFSISGENSHVVMIAISAAVAIIVLTVVTYVLVGRFCGYHKSKHSAEEKRLHFGNGHLKLPGLRTYVDPHTYEDPTQAVHEFAKELDATNISIDKVVGAGEFGEVCSGRLKLPSKKEISVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPEMIVTEYMENGSLDSFLRKHDAQFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTSPEAMSYRKFTSASDVWSYGIVLWEVMSYGERPYSQMSNQDVIKAVDERYRLPPPMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILDKLIRNPGSLKIITSAAARPSNLLLDQSNVDIATFHTTGDWLNGMRTAHCKEIFTGVEYSSCDTIAKISTDDMKKVGVTVVGPQKKIISTIKALETQSKNGPVPV
Tissue specificity：Greatest levels of expression occurring in the brain, also detected in testis. Expressed in myogenic progenitor cells (PubMed:27446912). {ECO:0000269|PubMed:27446912}.
Induction：
Developmental stage：Specifically expressed in heart during its development by mesenchymal cells of the endocardial cushions. Expressed in motor neurons at 11.5 dpc. In myogenic progenitor cells, highly expressed, at least as early as 11.5 dpc, expression decreases until 4 weeks after birth (PubMed:27446912). {ECO:0000269|PubMed:14585969, ECO:0000269|PubMed:17046737, ECO:0000269|PubMed:27446912}.
Protein families：Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily