MKRN1_MOUSE   Q9QXP6


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UniProt:Q9QXP6

Recommended name:E3 ubiquitin-protein ligase makorin-1

EC number:EC 2.3.2.27

Alternative names:(RING-type E3 ubiquitin transferase makorin-1)

Cleaved into:

GeneID:

Gene names  (primary ):Mkrn1

Gene names  (synonym ):

Gene names  (ORF ):

Length:481

Mass:53008

Sequence:MAEAAAPGTTATTSGAGAAAAAVAAASLTSIPTVAAPSPGAGGGGGGSDGSGGGWTKQVTCRYFMHGVCKEGDNCRYSHDLSDSPYGVVCKYFQRGYCVYGDRCRYEHSKPLKQEEVTATDLSAKPSLAASSSLSSGVGSLAEMNSGEAESRNPSFPTVGAGSEDWVNAIEFVPGQPYCGRTAPSCTEVPPQGSVTKEESEKEPTTVETKKQLCPYAAVGECRYGENCVYLHGDSCDMCGLQVLHPVDAAQRSQHIKSCIEAHEKDMELSFAVQRTKDMVCGICMEVVYEKANPSERRFGILSNCNHTYCLKCIRKWRSAKQFESKIIKSCPECRITSNFVIPSEYWVEEKEEKQKLIQKYKEAMSNKACRYFDEGRGSCPFGGNCFYKHAYPDGRREEPQRQKVGTSSRYRAQRRSHFWELIEERENNPFDNDEEEVVTFELGEMLLMLLAAGGDDELTDSEDEWDLFHDELEDFYDLDL

Tissue specificity:Highly expressed in embryo, in specific cell types of the central nervous system, in brain with the strongest levels of expression in the mantle layers and in testis. Moderate to low levels in somatic tissues. {ECO:0000269|PubMed:10843807, ECO:0000269|PubMed:12721631, ECO:0000269|PubMed:12971993}.

Induction:

Developmental stage:Not detected until 11 dpc. Restricted to developing central nervous system in 13 days embryos. {ECO:0000269|PubMed:10843807}.

Protein families:


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