ADA10_MOUSE O35598
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UniProt:O35598
Recommended name：Disintegrin and metalloproteinase domain-containing protein 10
EC number：EC 3.4.24.81
Alternative names：(ADAM 10) (Kuzbanian protein homolog) (Mammalian disintegrin-metalloprotease) (CD antigen CD156c)
Cleaved into：
GeneID：11487
Gene names (primary )：Adam10
Gene names (synonym )：Kuz Madm
Gene names (ORF )：
Length：749
Mass：83968
Sequence：MVLPTVLILLLSWAAGLGGQYGNPLNKYIRHYEGLSYNVDSLHQKHQRAKRAVSHEDQFLLLDFHAHGRQFNLRMKRDTSLFSDEFKVETSNKVLDYDTSHIYTGHIYGEEGSFSHGSVIDGRFEGFIKTRGGTFYIEPAERYIKDRILPFHSVIYHEDDINYPHKYGPQGGCADHSVFERMRKYQMTGVEEGARAHPEKHAASSGPELLRKKRTTLAERNTCQLYIQTDHLFFKYYGTREAVIAQISSHVKAIDTIYQTTDFSGIRNISFMVKRIRINTTSDEKDPTNPFRFPNIGVEKFLELNSEQNHDDYCLAYVFTDRDFDDGVLGLAWVGAPSGSSGGICEKSKLYSDGKKKSLNTGIITVQNYGSHVPPKVSHITFAHEVGHNFGSPHDSGTECTPGESKNLGQKENGNYIMYARATSGDKLNNNKFSLCSIRNISQVLEKKRNNCFVESGQPICGNGMVEQGEECDCGYSDQCKDDCCFDANQPEGKKCKLKPGKQCSPSQGPCCTAQCAFKSKSEKCRDDSDCAKEGICNGFTALCPASDPKPNFTDCNRHTQVCINGQCAGSICEKYDLEECTCASSDGKDDKELCHVCCMKKMAPSTCASTGSLQWSKQFSGRTITLQPGSPCNDFRGYCDVFMRCRLVDADGPLARLKKAIFSPQLYENIAEWIVAHWWAVLLMGIALIMLMAGFIKICSVHTPSSNPKLPPPKPLPGTLKRRRPPQPIQQPPRQRPRESYQMGHMRR
Tissue specificity：Expressed in the brain, specifically in neurons and astrocytes (at protein level) (PubMed:23676497, PubMed:29325091). Expressed in inner and outer pillar cells of the organ of Corti (at protein level) (PubMed:30639848). Expressed in kidney and lung (PubMed:30463011). {ECO:0000269|PubMed:23676497, ECO:0000269|PubMed:29325091, ECO:0000269|PubMed:30463011, ECO:0000269|PubMed:30639848}.
Induction：
Developmental stage：Widely expressed in the nervous system at 18 dpc, with high expression in the posterior midbrain, which diminished toward the anterior midbrain.
Protein families：