UCMA_MOUSE Q14BU0
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UniProt:Q14BU0
Recommended name:Unique cartilage matrix-associated protein
EC number:
Alternative names:(Upper zone of growth plate and cartilage matrix associated protein)
Cleaved into:Unique cartilage matrix-associated protein C-terminal fragment (Ucma-C) (Gla-rich protein) (GRP)
GeneID:68527
Gene names (primary ):Ucma
Gene names (synonym ):
Gene names (ORF ):
Length:138
Mass:16579
Sequence:MSWRRVILLSSLLALVLLCMLQEGTSASVGSRQAAAEGVQEGVKQKIFMQESDASNFLKRRGKRSPKSRDEVNAENRQRLRDDELRREYYEEQRNEFENFVEEQRDEQEERTREAVEQWRQWHYDGLYPSYLYNRQNI
Tissue specificity:Predominantly expressed in resting chondrocytes. {ECO:0000269|PubMed:18156182}.
Induction:Expression inhibited by TGFB1, and weakly inhibited by BMP2. {ECO:0000269|PubMed:19819238}.
Developmental stage:Transiently expressed in the developing mouse skeleton between day 13.5 dpc of embryonic development and 5 months of postnatal development. Absent in undifferentiated mesenchymal cells. Isoforms 1 and 3 are significantly increased with the onset of chondrogenesis, whereas Isoforms 2 and 4 are detected at a later stage. {ECO:0000269|PubMed:18156182, ECO:0000269|PubMed:19819238}.
Protein families:UCMA family