VRK3_MOUSE Q8K3G5
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UniProt:Q8K3G5
Recommended name:Inactive serine/threonine-protein kinase VRK3
EC number:
Alternative names:(Serine/threonine-protein pseudokinase VRK3) (Vaccinia-related kinase 3)
Cleaved into:
GeneID:101568
Gene names (primary ):Vrk3
Gene names (synonym ):
Gene names (ORF ):
Length:453
Mass:50830
Sequence:MISFCPVCGKSVKVSFKFCPYCGKALPVEEDGGTQSAVTPHVSSVPGSRRDLNSSFETSPKKVKCSHTVTSLPLSRHSDCDSSGSDNTLTSPDRATGTRSRPLTPKGSPLSNRQSPQTLKRTRVTTSLQALATGTELTDQNGKHWTLGALQIRDDQGILYEAEPTSAVPSESRTQKWRFSLKLDSKDGRLFNEQNFFQRVAKPLQVNKWKKQFLLPLLAIPTCIGFGIHQDKYRFLVFPSLGRSLQSALDDNPKHVVSERCVLQVACRLLDALEYLHENEYVHGNLTAENVFVNPEDLSQVTLVGYGFTYRYCPGGKHVAYKEGSRSPHDGDLEFISMDLHKGCGPSRRSDLQTLGYCMLKWLYGSLPWTNCLPNTEKITRQKQKYLDSPERLVGLCGRWNKASETLREYLKVVMALNYEEKPPYATLRNSLEALLQDMRVSPYDPLDLQMVP
Tissue specificity:Expressed in liver, kidney, muscle, thymus, and bone marrow. Weakly expressed in spleen. {ECO:0000269|PubMed:12782311}.
Induction:
Developmental stage:Weakly expressed in embryo compared to VRK1 and VRK3. Expressed from 10.5 dpc to 13.5 dpc in developing liver and then decreases. It increases again from 17.5 dpc and remains thereafter. Highly expressed in hematopoietic embryonic tissues from 10.5 dpc to 14.5 dpc. Strongly expressed in the yolk-sac. {ECO:0000269|PubMed:12782311}.
Protein families:Protein kinase superfamily, CK1 Ser/Thr protein kinase family, VRK subfamily