VRK3_MOUSE   Q8K3G5


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UniProt:Q8K3G5

Recommended name:Inactive serine/threonine-protein kinase VRK3

EC number:

Alternative names:(Serine/threonine-protein pseudokinase VRK3) (Vaccinia-related kinase 3)

Cleaved into:

GeneID:101568

Gene names  (primary ):Vrk3

Gene names  (synonym ):

Gene names  (ORF ):

Length:453

Mass:50830

Sequence:MISFCPVCGKSVKVSFKFCPYCGKALPVEEDGGTQSAVTPHVSSVPGSRRDLNSSFETSPKKVKCSHTVTSLPLSRHSDCDSSGSDNTLTSPDRATGTRSRPLTPKGSPLSNRQSPQTLKRTRVTTSLQALATGTELTDQNGKHWTLGALQIRDDQGILYEAEPTSAVPSESRTQKWRFSLKLDSKDGRLFNEQNFFQRVAKPLQVNKWKKQFLLPLLAIPTCIGFGIHQDKYRFLVFPSLGRSLQSALDDNPKHVVSERCVLQVACRLLDALEYLHENEYVHGNLTAENVFVNPEDLSQVTLVGYGFTYRYCPGGKHVAYKEGSRSPHDGDLEFISMDLHKGCGPSRRSDLQTLGYCMLKWLYGSLPWTNCLPNTEKITRQKQKYLDSPERLVGLCGRWNKASETLREYLKVVMALNYEEKPPYATLRNSLEALLQDMRVSPYDPLDLQMVP

Tissue specificity:Expressed in liver, kidney, muscle, thymus, and bone marrow. Weakly expressed in spleen. {ECO:0000269|PubMed:12782311}.

Induction:

Developmental stage:Weakly expressed in embryo compared to VRK1 and VRK3. Expressed from 10.5 dpc to 13.5 dpc in developing liver and then decreases. It increases again from 17.5 dpc and remains thereafter. Highly expressed in hematopoietic embryonic tissues from 10.5 dpc to 14.5 dpc. Strongly expressed in the yolk-sac. {ECO:0000269|PubMed:12782311}.

Protein families:Protein kinase superfamily, CK1 Ser/Thr protein kinase family, VRK subfamily