AURKB_MOUSE O70126
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UniProt:O70126
Recommended name:Aurora kinase B
EC number:EC 2.7.11.1
Alternative names:(Aurora 1) (Aurora- and IPL1-like midbody-associated protein 1) (Aurora/IPL1-related kinase 2) (ARK-2) (Aurora-related kinase 2) (STK-1) (Serine/threonine-protein kinase 12) (Serine/threonine-protein kinase 5) (Serine/threonine-protein kinase aurora-B)
Cleaved into:
GeneID:20877
Gene names (primary ):Aurkb
Gene names (synonym ):Aik2 Aim1 Airk2 Ark2 Stk1 Stk12 Stk5
Gene names (ORF ):
Length:345
Mass:39384
Sequence:MAQKENAYPWPYGSKTSQSGLNTLSQRVLRKEPATTSALALVNRFNSQSTAAPGQKLAENKSQGSTASQGSQNKQPFTIDNFEIGRPLGKGKFGNVYLAREKKSRFIVALKILFKSQIEKEGVEHQLRREIEIQAHLKHPNILQLYNYFYDQQRIYLILEYAPRGELYKELQKSRTFDEQRTATIMEELSDALTYCHKKKVIHRDIKPENLLLGLQGELKIADFGWSVHAPSLRRKTMCGTLDYLPPEMIEGRMHNEMVDLWCIGVLCYELMVGNPPFESPSHSETYRRIVKVDLKFPSSVPSGAQDLISKLLKHNPWQRLPLAEVAAHPWVRANSRRVLPPSAL
Tissue specificity:Expressed in testis, intestine and spleen. All of them are tissues that contain a large number of proliferating cells. Expressed during S phase, in a cell-cycle-dependent fashion.
Induction:
Developmental stage:Strongly expressed in 8.5 and 12.5 dpc.
Protein families:Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily