Product List

alpha Synuclein Rabbit Monoclonal Antibody

Size:50μL Price:$158
Size:100μL Price:$288
Size:200μL Price:$520
Application:WB,IHC,IP
Reactivity:Human,Rat
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:SNCA

SKU: AMRe01639

Detail

Summary

Production Name	alpha Synuclein Rabbit Monoclonal Antibody
Description	Recombinant rabbit monoclonal antibody
Host	Rabbit
Application	WB,IHC,IP
Reactivity	Human,Rat

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	IgG
Clonality	Monoclonal
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Purification	Affinity Purification

Immunogen

Gene Name	SNCA
Alternative Names	SNCA; NACP; PARK1; Alpha-synuclein; Non-A beta component of AD amyloid; Non-A4 component of amyloid precursor; NACP
Gene ID	6622
SwissProt ID	P37840

Application

Dilution Ratio	WB 1:500-1:1000,IHC 1:50-1:100,IP 1:20-1:50
Molecular Weight	Calculated MW: 14 kDa; Observed MW: 18 kDa

Background

May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation. Genetic alterations of SNCA resulting in aberrant polymerization into fibrils, are associated with several neurodegenerative diseases (synucleinopathies).

Research Area

Neuroscience