Phospho-Nrf2 (Ser40) Rabbit Monoclonal Antibody

Phospho-Nrf2 (Ser40) Rabbit Monoclonal Antibody

Size1:50μl Price1:$188
Size2:100μl Price2:$338
Size3:500μl Price3:$1200
SKU: AMRe03900 Category: Rabbit Monoclonal Antibody Tags: , , ,

Datasheet

Summary

Production Name

Phospho-Nrf2 (Ser40) Rabbit Monoclonal Antibody

Description

Recombinant Rabbit Monoclonal antibody

Host

Rabbit

Application

WB

Reactivity

Human

 

Performance

Conjugation

Unconjugated

Modification

Phosphorylated

Isotype

IgG

Clonality

Monoclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Purification

Affinity Chromatography

 

Immunogen

Gene Name

NFE2L2

Alternative Names

NFE2L2; NRF2; Nuclear factor erythroid 2-related factor 2; NF-E2-related factor 2; NFE2-related factor 2; HEBP1; Nuclear factor; erythroid derived 2; like 2

Gene ID

4780

SwissProt ID

Q16236

 

Application

Dilution Ratio

WB: 1/500-1/1000

Molecular Weight

Calculated MW: 68 kDa; Observed MW: 90 kDa

 

Background

Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region.

 

Research Area

Epigenetics and Nuclear Signaling