Product List

HMGB1 Rabbit Monoclonal antibody

Size:50μL Price:158 $99
Size:100μL Price:288 $180
Application:WB,IHC
Reactivity:Human,Mouse,Rat
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:HMGB1

SKU: AMRe03744

Detail

Summary

Production Name	HMGB1 Rabbit Monoclonal antibody
Description	Recombinant rabbit monoclonal antibody
Host	Rabbit
Application	WB,IHC
Reactivity	Human,Mouse,Rat

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	IgG
Clonality	Monoclonal Antibody
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Purification	Affinity Purified

Immunogen

Gene Name	HMGB1
Alternative Names	HMGB1; HMG1; High mobility group protein B1; High mobility group protein 1; HMG-1
Gene ID	3146
SwissProt ID	P09429

Application

Dilution Ratio	WB 1:500-1:1000,IHC 1:50-1:100
Molecular Weight	Calculated MW: 25 kDa; Observed MW: 25 kDa

Background

High mobility group (HMG) proteins 1 and 2 are ubiquitous non-histone components of chromatin. Evidence suggests that the binding of HMG proteins to DNA induces alterations in the DNA architecture including DNA bending and unwinding of the helix. HMG proteins synergize with Oct-2, members of the NFκB family, ATF-2 and c-Jun to activate transcription.

Research Area

Epigenetics and Nuclear Signaling