Summary
| Production Name | GSK3 beta Rabbit Monoclonal Antibody |
| Description | Recombinant Rabbit Monoclonal antibody |
| Host | Rabbit |
| Application | WB,IHC |
| Reactivity | Human,Rat,Hamster |
Performance
| Conjugation | Unconjugated |
| Modification | Unmodified |
| Isotype | IgG |
| Clonality | Monoclonal Antibody |
| Form | Liquid |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Buffer | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Purification | Affinity Purified |
Immunogen
| Gene Name | GSK3B |
| Alternative Names | GSK3B; Glycogen synthase kinase-3 beta; GSK-3 beta; Serine/threonine-protein kinase GSK3B |
| Gene ID | 2932 |
| SwissProt ID | P49841 |
Application
| Dilution Ratio | WB: 1/500-1/1000 IHC: 1/50-1/100 |
| Molecular Weight | Calculated MW: 47 kDa; Observed MW: 47 kDa |
Background
Glycogen synthase kinase-3 (GSK3) is a proline-directed serine-threonine kinase that was initially identified as a phosphorylating and inactivating glycogen synthase .GSK3B is involved in energy metabolism, neuronal cell development, and body pattern formation.In skeletal muscle, it contributes to insulin regulation of glycogen synthesis by phosphorylating and inhibiting GYS1 activity and hence glycogen synthesis.
Research Area
Neuroscience
