Product List

Phospho-p53 (Ser392) Rabbit Monoclonal Antibody

Size:50μL Price:$168
Size:100μL Price:$300
Size:200μL Price:$520
Application:WB,IHC,IP
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:TP53

SKU: AMRe03901

Detail

Summary

Production Name	Phospho-p53 (Ser392) Rabbit Monoclonal Antibody
Description	Recombinant rabbit monoclonal antibody
Host	Rabbit
Application	WB,IHC,IP
Reactivity	Human, Mouse, Rat

Performance

Conjugation	Unconjugated
Modification	Phosphorylated
Isotype	IgG
Clonality	Monoclonal
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% protective protein.
Purification	Affinity Purification

Immunogen

Gene Name	TP53
Alternative Names	TP53; P53; Cellular tumor antigen p53; Antigen NY-CO-13; Phosphoprotein p53; Tumor suppressor p53
Gene ID	7157
SwissProt ID	P04637

Application

Dilution Ratio	WB 1:500-1:1000,IHC 1:50-1:100,IP 1:20-1:50
Molecular Weight	Calculated MW:44 kDa;Observed MW: 53 kDa

Background

Tumor protein p53, a nuclear protein, plays an essential role in the regulation of cell cycle, specifically in the transition from G0 to G1. It is found in very low levels in normal cells, however, in a variety of transformed cell lines, it is expressed in high amounts, and believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing DNA-binding, oligomerization and transcription activation domains.

Research Area

Cell Biology