Name: MLH1 Rabbit Monoclonal antibody
Brand: Enkilife Limited
SKU: AMRe01485
Price: 158 USD
Availability: InStock
Rating: 5 (1 reviews)

MLH1 Rabbit Monoclonal antibody

Size:50μL Price:158 $99
Size:100μL Price:288 $180
Application:WB,ICC/IF,IP
Reactivity:Human,Mouse,Rat
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:MLH1

SKU: AMRe01485

Detail

Summary

Production Name	MLH1 Rabbit Monoclonal antibody
Description	Recombinant rabbit monoclonal antibody
Host	Rabbit
Application	WB,ICC/IF,IP
Reactivity	Human,Mouse,Rat

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	IgG
Clonality	Monoclonal Antibody
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Purification	Affinity Purified

Immunogen

Gene Name	MLH1
Alternative Names	MLH1; COCA2; DNA mismatch repair protein Mlh1; MutL protein homolog 1
Gene ID	4292
SwissProt ID	P40692

Application

Dilution Ratio	WB 1:500-1:1000,ICC/IF 1:50-1:200,IP 1:20-1:50
Molecular Weight	Calculated MW: 85 kDa; Observed MW: 85 kDa

Background

This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Alternatively spliced transcript variants encoding different isoforms have been described, but their full-length natures have not been determined.

Research Area

Epigenetics and Nuclear Signaling